Evidence map›Paper›PMID 31502509›Full record

ArticleJournal of child neurology2019

Disparities in Pediatric Epilepsy Remission Are Associated With Race and Ethnicity.

Celestine H Yeung Gregerson, Amanda V Bakian, Jacob Wilkes, Andrew J Knighton, Flory Nkoy, Matthew Sweney, Francis M Filloux, Joshua L Bonkowsky

Open access · bronzeAbstract read
In one paragraph

Article in Journal of child neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 39 citations in OpenAlex.

  1. Surgical re-evaluation patterns among pediatric vagus nerve stimulation non-responders: a single-center retrospective study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Disparities in seizure outcomes revealed by large language models.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  8. Review
  9. Anti-seizure Medications: Challenges and Opportunities.CNS & neurological disorders drug targets · 2024
    Review
  10. Inequities in Epilepsy: A Scoping Review.Neurology. Clinical practice · 2023
    Article
  11. Article
  12. Diversity, Equity, and Inclusion within Pediatric Adherence Science.Journal of clinical psychology in medical settings · 2023
    Article
  13. Article
  14. Article
  15. Observational
  16. Treatment gaps in epilepsy.Frontiers in epidemiology · 2022
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Celestine H Yeung GregersonSchool of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
Amanda V BakianDepartment of Psychiatry, Salt Lake City, UT, USA.
Jacob WilkesIntermountain Healthcare, Salt Lake City, UT, USA.
Andrew J KnightonIntermountain Healthcare, Salt Lake City, UT, USA.
Flory NkoyDivision of Inpatient Medicine, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Matthew SweneyDivision of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Francis M FillouxDivision of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Joshua L BonkowskyDivision of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.ORCID 0000-0001-8775-147X
University of Utah · USIntermountain Healthcare · USPrimary Children's Hospital · US

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
NCATS NIH HHS UL1 TR002538
6 · The paper itself

Abstract

objectiveThe purpose of our study was to assess whether race/ethnicity was associated with seizure remission in pediatric epilepsy.

methodsThis was a retrospective population-based cohort study of children who were evaluated for new-onset epilepsy in the clinic, emergency department, and/or hospital by a pediatric neurologist in an integrated health care delivery system. Children were between ages 6 months and 15 years at their initial presentation of epilepsy. The cohort, identified through an electronic database, was assembled over 6 years, with no less than 5 years of follow-up. All children were evaluated for race, ethnicity, insurance type, and socioeconomic background. Patient outcome was determined at the conclusion of the study period and categorized according to their epilepsy control as either drug resistant (pharmacoresistant and intractable) or drug responsive (controlled, probable remission, and terminal remission).

resultsIn the final cohort of 776 patients, 63% were drug responsive (control or seizure remission). After controlling for confounding socioeconomic and demographic factors, children of Hispanic ethnicity experienced reduced likelihood (hazard) of drug-responsive epilepsy (hazard ratio 0.6, SIGNIFICANCE: We found that Hispanic ethnicity is associated with a reduced likelihood of achieving seizure control and remission. This study suggests that factors associated with the race/ethnicity of patients contributes to their likelihood of achieving seizure freedom.

Indexed as

EpilepsyHealth Status DisparitiesAdolescentChildChild, PreschoolDatabases, FactualEthnicityFemaleHealth Care CostsHispanic or LatinoHumansInfantInsurance, HealthMaleRemission InductionRetrospective Studiesepilepsyhealth disparitiesminoritypediatric

Identifiers

PMID31502509
PMCPMC6842107
OpenAlexW2972502587

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.