SynthesisCognitive, affective & behavioral neuroscience2019
Neural correlates of aversive anticipation: An activation likelihood estimate meta-analysis across multiple sensory modalities.
Synthesis in Cognitive, affective & behavioral neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Structural and functional brain abnormal alteration in patients with type 2 diabetes mellitus: A coordinate-based meta-analysis.Translational psychiatry · 2025Pooled it
- Altered anticipatory brain responses in eating disorders: A neuroimaging meta-analysis.European eating disorders review : the journal of the Eating Disorders Association · 2023Pooled it
- The neuroscience of social feelings: mechanisms of adaptive social functioning.Neuroscience and biobehavioral reviews · 2021Pooled it
- Contingency awareness shapes neural responses in fear conditioning.Neuroscience of consciousness · 2026Article
- Using Tangible User Interfaces (TUIs): Preliminary Evidence on Memory and Comprehension Skills in Children with Autism Spectrum Disorder.Behavioral sciences (Basel, Switzerland) · 2025Article
- How Distributed Subcortical Integration of Reward and Threat May Inform Subsequent Approach-Avoidance Decisions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition.Brain structure & function · 2024Review
- A three-dimensional model of neural activity and phenomenal-behavioral patterns.Molecular psychiatry · 2024Review
- How Instructions, Learning, and Expectations Shape Pain and Neurobiological Responses.Annual review of neuroscience · 2023Review
- Win and Loss Responses in the Monetary Incentive Delay Task Mediate the Link between Depression and Problem Drinking.Brain sciences · 2022Article
- Coping With Anxiety: Brain Structural Correlates of Vigilance and Cognitive Avoidance.Frontiers in psychiatry · 2022Article
- Threat imminence reveals links among unfolding of anticipatory physiological response, cortical-subcortical intrinsic functional connectivity, and anxiety.Neurobiology of stress · 2022Article
- Anticipating control over aversive stimuli is mediated by the medial prefrontal cortex: An fMRI study with healthy adults.Human brain mapping · 2021Article
- Threat-anticipatory psychophysiological response is enhanced in youth with anxiety disorders and correlates with prefrontal cortex neuroanatomy.Journal of psychiatry & neuroscience : JPN · 2021Article
- Article
- Threat bias and resting state functional connectivity of the amygdala and bed nucleus stria terminalis.Journal of psychiatric research · 2020Article
- Non-invasive cervical vagus nerve stimulation effects on reaction time and valence image anticipation response.Brain stimulationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anticipation is a universal preparatory response essential to the survival of an organism. Although meta-analytic synthesis of the literature exists for the anticipation of reward, a neuroimaging-based meta-analysis of the neural mechanisms of aversive anticipation is lacking. To address this gap in the literature, we ran an activation likelihood estimate (ALE) meta-analysis of 63 fMRI studies of aversive anticipation across multiple sensory modalities. Results of the ALE meta-analysis provide evidence for a core circuit involved in aversive anticipation, including the anterior insula, anterior cingulate cortex, mid-cingulate cortex, amygdala, thalamus, and caudate nucleus among other regions. Direct comparison of aversive anticipation studies using tactile versus visual stimuli identified additional regions involved in sensory specific aversive anticipation across these sensory modalities. Results from complementary multi-study voxel-wise and NeuroSynth analyses generally provide converging evidence for a core circuit involved in aversive anticipation. The multi-study voxel-wise analyses also implicate a more widespread preparatory response across sensory, motor, and cognitive control regions during more prolonged periods of aversive anticipation. The potential roles of these structures in anticipatory processing as well as avenues for future research are discussed.
Indexed as
Identifiers
31502205What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.