ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020
Relationships between cognition, function, and quality of life among HIV+ Canadian men.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Health-related quality of life measures provide information on the contributors, components, and consequences of frailty in HIV: a systematic mapping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Pooled it
- Effects of aerobic exercise on quality of life of people with HIV-associated neurocognitive disorder on antiretroviral therapy: a randomised controlled trial.BMC infectious diseases · 2022Trial
- Evidence that intrinsic brain connectivity moderates the association between gait and neurocognitive function in people living with HIV.Journal of neurovirology · 2026Article
- Sedative co-medication patterns across frailty states in people with HIV: a network-based study.International journal of clinical pharmacy · 2025Article
- Study characteristics on health-related quality of life in older people living with human immunodeficiency virus: A narrative review.World journal of virology · 2025Article
- The relationship between social network size and brain structure in older adults living with HIV.Brain imaging and behavior · 2025Article
- Using network analysis to provide evidence for brain health as a unified construct relevant to aging with HIV.Social psychiatry and psychiatric epidemiology · 2025Article
- The Patient Generated Index (PGI) as an early-warning system for predicting brain health challenges: a prospective cohort study for people living with Human Immunodeficiency Virus (HIV).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Determinants of semantic and episodic memory decline among older adults in Ghana: Evidence from the WHO study on global AGEing and adult health Ghana wave 2.Dialogues in health · 2023Article
- Translocation of bacterial LPS is associated with self-reported cognitive abilities in men living with HIV receiving antiretroviral therapy.AIDS research and therapy · 2023Article
- Syndemic conditions and quality of life in the PISCIS Cohort of people living with HIV in Catalonia and the Balearic Islands: a cross sectional study.Health and quality of life outcomes · 2023Article
- Development of a Prototype for a Bilingual Patient-Reported Outcome Measure of the Important Health Aspects of Quality of Life in People Living with HIV: The Preference Based HIV Index (PB-HIV).Journal of personalized medicine · 2022Article
- A longitudinal view of successful aging with HIV: role of resilience and environmental factors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Relationship between reward-related evoked potentials and real-world motivation in older people living with human immunodeficiency virus.Frontiers in aging neuroscience · 2022Article
- Cognitive Impairment in Non-critical, Mild-to-Moderate COVID-19 Survivors.Frontiers in psychology · 2022Article
- A Short-term Psychological Intervention for People Living with HIV During the First Wave of COVID-19.International journal of cognitive therapy · 2022Article
- Development and usability of a feedback tool, "My Personal Brain Health Dashboard", to improve setting of self-management goals among people living with HIV in Canada.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Action for better brain health among people living with HIV: protocol for a randomized controlled trial.BMC infectious diseases · 2021Article
- Article
- Neurocognitive impairment and health-related quality of life among people living with Human Immunodeficiency Virus (HIV).PloS one · 2021Observational
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
objectiveTo estimate the extent to which HIV-related variables, cognition, and other brain health factors interrelate with other HIV-associated symptoms to influence function, health perception, and QOL in older HIV+ men in Canada.
designCross-sectional structural equation modelling (SEM) of data from the inaugural visit to the Positive Brain Health Now Cohort.
settingHIV clinics at 5 Canadian sites. SUBJECTS: 707 men, age ≥ 35 years, HIV+ for at least one year, without clinically diagnosed dementia.
main outcome measuresFive latent and 21 observed variables from the World Health Organization's biopsychosocial model for functioning and disability and the Wilson-Cleary Model were analysed. SEM was used to link disease factors to symptoms, impairments, function, health perception, and QOL with a focus on cognition.
resultsQOL was explained directly by depression, social role, health perception, social support, and quality of the environment. Measured cognitive performance had direct effects on activity/function and indirect effects on participation, HP and QOL, acting through self-reported cognitive difficulties and meaningful activities.
conclusionThe biopsychosocial model showed good fit, with RMSEA < 0.05. This is the first time the full model has been tested in HIV. All of the domains included in the model are theoretically amenable to intervention and many have evidence-based interventions that could be harnessed to improve QOL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.