Evidence map›Paper›PMID 31502104›Full record

ArticleJournal of gastrointestinal cancer2020

The Improvement in 1-Year Survival Rate of Patients with Hepatocellular Carcinoma BCLC Stage A and B after the Implementation of Comprehensive Management.

Juferdy Kurniawan, Rino A Gani, Irsan Hasan, Andri S Sulaiman, Cosmas R A Lesmana, Chyntia O M Jasirwan, Kemal F Kalista, Saut H H Nababan, Steven Zulkifly

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Juferdy KurniawanHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No. 71, Senen, Central Jakarta, 10430, Indonesia. juferdy.k@gmail.com.
Rino A GaniHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No. 71, Senen, Central Jakarta, 10430, Indonesia.
Irsan HasanHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No. 71, Senen, Central Jakarta, 10430, Indonesia.
Andri S SulaimanHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No. 71, Senen, Central Jakarta, 10430, Indonesia.
Cosmas R A LesmanaHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No. 71, Senen, Central Jakarta, 10430, Indonesia.
Chyntia O M JasirwanHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No. 71, Senen, Central Jakarta, 10430, Indonesia.
Kemal F KalistaHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No. 71, Senen, Central Jakarta, 10430, Indonesia.
Saut H H NababanHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No. 71, Senen, Central Jakarta, 10430, Indonesia.
Steven ZulkiflyHepatobiliary Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jl. Diponegoro No. 71, Senen, Central Jakarta, 10430, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe previous study showed lack of improvement in survival rate of hepatocellular carcinoma (HCC) patients in 2013-2014 period compared to 1998-1999 period in Indonesia due to late diagnosis. Comprehensive management of HCC has been implemented since 2015 in Cipto Mangunkusumo National General Hospital. This aims to provide better screening and surveillance in HCC patients and prioritizing of more proactive approach, such as online patient's group discussion and social media education.

aimTo compare the survival rates in HCC BCLC stage A and B before and after the implementation of comprehensive management.

methodsA retrospective study design was conducted in this study. We compared the database of HCC BCLC A and B patients between the 2015-2017 period and the 2013-2014 period. Clinical parameters, modality of treatment, and 1-year survival rate were analyzed.

resultsA total of 50 patients from 2013 to 2014 period and 143 patients from 2015 to 2017 period were included in this study. After the implementation of comprehensive management, the number of patients detected in BCLC class A increased significantly (p = 0.003). In 2015-2017 period, the number of patients that received curative treatment increased significantly (p = 0.018). The 1-year survival rate of the 2015-2017 group and the 2013-2014 group was 73.9% and 47.9%, respectively, with p value 0.002.

conclusionsThe 1-year survival rate of BCLC A and BCLC B HCC patients in Cipto Mangunkusumo National Hospital improved significantly after the implementation of comprehensive management of HCC in 2015.

Indexed as

Early Detection of CancerAdultAgedAged, 80 and overCarcinoma, HepatocellularComprehensive Health CareFemaleHealth Plan ImplementationHumansIndonesiaKaplan-Meier EstimateLiver NeoplasmsMaleMass ScreeningMiddle AgedNeoplasm StagingComprehensive managementCurativeHepatectomyHepatocellular carcinomaRadiofrequency ablationSurveillanceSurvival rate

Identifiers

PMID31502104

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.