Evidence map›Paper›PMID 31502032›Full record

Trial reportWorld journal of urology2020

Holmium laser enucleation of the prostate versus thulium laser enucleation of the prostate for the treatment of large-volume prostates > 80 ml: 18-month follow-up results.

Junjie Zhang, Zhenyu Ou, Xiaobo Zhang, Wei He, Ruizhe Wang, Miao Mo, Lingxiao Chen, Ran Xu, Shusuan Jiang, Xiaoyan Peng and 2 more

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Junjie ZhangDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Zhenyu OuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Xiaobo ZhangDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Wei HeDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Ruizhe WangDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Miao MoDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Lingxiao ChenDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Ran XuDepartment of Urology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
Shusuan JiangDepartment of Urology, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medical, Central South University, Changsha, 410013, Hunan, China.
Xiaoyan PengDepartment of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Lin QiDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Long WangDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. wanglong@csu.edu.cn.ORCID http://orcid.org/0000-0003-4583-2428
Central South University · CN

Funding

National Natural Science Foundation of China 81770758
6 · The paper itself

Abstract

purposeTo compare the perioperative and functional outcomes of holmium laser enucleation of the prostate (HoLEP) and thulium laser enucleation of the prostate (ThuLEP) for the treatment of large-volume benign prostatic hyperplasia (BPH) (> 80 ml).

methodsA total of 116 consecutive patients with BPH were randomized to be treated surgically with either HoLEP (n = 58) or ThuLEP (n = 58), following the classical three-lobe enucleation technique. Follow-up was assessed at 1, 3, 6, 12 and 18 months after surgery.

resultsAt 18 months, the lower urinary tract symptom index was improved significantly in both groups compared with the baseline values. The operative time (78.4 ± 8.0 vs. 71.4 ± 6.4 min) and enucleation time (61.2 ± 5.4 vs. 56.4 ± 8.4 min) were significantly shorter for ThuLEP compared to HoLEP (both p < 0.001). There were no significant differences between the two groups regarding morcellation time, resected weight, hemoglobin decrease, catheter time and hospital stay (p > 0.05). The HoLEP and ThuLEP groups had equivalent International Prostate Symptom Scores (3 [3-3] vs. 3 [3-3], p = 0.776), quality of life (1 [1-2] vs. 2 [1-2], p = 0.809), Qmax (25.3 ± 4.8 ml/s vs. 24.7 ± 4.4 ml/s, p = 0.470), postvoid residual urine (PVR) (6.1 [2.6-20.8] vs. 7.7 [3.1-22.8] ml, p = 0.449) and PSA (0.84 ± 0.32 vs. 0.90 ± 0.34 ml, p = 0.309) at 18 months postoperatively.

conclusionBoth HoLEP and ThuLEP relieve lower urinary tract symptoms in a comparable way with high efficacy and safety. ThuLEP was statistically superior to HoLEP in operation time and enucleation time, although the differences were clinically negligible.

Indexed as

ThuliumAgedFollow-Up StudiesHumansLasers, Solid-StateLaser TherapyMaleOrgan SizeProstatectomyProstatic HyperplasiaTime FactorsTreatment OutcomeThuliumBenign prostatic hyperplasia (BPH)HoLEPLarge-volume prostateRandomized controlled trial (RCT)ThuLEP

Identifiers

PMID31502032
OpenAlexW2972721350

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.