Evidence map›Paper›PMID 31502014›Full record

Observational studyEuropean journal of nuclear medicine and molecular imaging2020

Early effects of transcatheter aortic valve replacement on cardiac sympathetic nervous function assessed by

Yoshito Kadoya, Kan Zen, Nagara Tamaki, Nobuyasu Ito, Kensuke Kuwabara, Michiyo Yamano, Tetsuhiro Yamano, Takeshi Nakamura, Shigenori Matsushima, Katsuhiko Oka and 3 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Observational
  9. Serial changes in cardiac sympathetic nervous function after transcatheter aortic valve replacement: A prospective observational study usingJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Observational
  10. Prognostic value of cardiacESC heart failure · 2021
    Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Yoshito KadoyaDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Kan ZenDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan. k-zen@koto.kpu-m.ac.jp.ORCID 0000-0002-3119-2485
Nagara TamakiDepartment of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Nobuyasu ItoDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Kensuke KuwabaraDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Michiyo YamanoDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Tetsuhiro YamanoDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Takeshi NakamuraDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Shigenori MatsushimaDepartment of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Katsuhiko OkaDepartment of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Satoshi NumataDepartment of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hitoshi YakuDepartment of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Satoaki MatobaDepartment of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Kyoto Prefectural University of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe effects of transcatheter aortic valve replacement (TAVR) on cardiac sympathetic nervous (CSN) function have not been fully explored. This study aimed to investigate the early (within 2 weeks) effects of TAVR on CSN function in patients with severe aortic valve stenosis (AS) using

methodsOf 143 consecutive patients who were scheduled to undergo TAVR, 67 (18 men; median age 86 years) were evaluated in this single-centre prospective observational study. MIBG scintigraphy was performed at baseline and 3-14 days after the TAVR procedure to evaluate the heart-mediastinum ratio (H/M) and washout rate (WR). Differences between baseline and post-TAVR MIBG parameters were analysed. MIBG parameter changes were compared with echocardiographic parameters. Furthermore, factors involved in the improvement in MIBG parameters were investigated.

resultsAll patients successfully underwent TAVR with improved echocardiographic parameters, including aortic valve area (AVA; 0.6 cm

conclusionsThe CSN function was impaired in patients with AS, as assessed using MIBG scintigraphy. WR and delayed H/M improved immediately after TAVR. Improvement in CSN function may be related to echocardiographic AS severity at baseline before TAVR.

Indexed as

Aortic Valve StenosisHeartIodine RadioisotopesRadionuclide ImagingSympathetic Nervous SystemTranscatheter Aortic Valve Replacement3-IodobenzylguanidineAged, 80 and overFemaleHumansMaleSeverity of Illness IndexSex FactorsStroke VolumeTreatment OutcomeVentricular Function, Left3-IodobenzylguanidineIodine-123Iodine Radioisotopes123I-Metaiodobenzylguanidine scintigraphyAortic valve stenosisCardiac sympathetic nervousTranscatheter aortic valve replacement

Identifiers

PMID31502014
OpenAlexW2973024500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.