Evidence map›Paper›PMID 31501929›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2019

Smartphone-based fundus photography for screening of plus-disease retinopathy of prematurity.

Tapan P Patel, Michael T Aaberg, Yannis M Paulus, Philip Lieu, Vaidehi S Dedania, Cynthia X Qian, Cagri G Besirli, Todd Margolis, Daniel A Fletcher, Tyson N Kim

Abstract read
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Smartphone-based retinal camera modified for ROP screening.International journal of retina and vitreous · 2025
    Article
  2. Review
  3. Review
  4. [Smartphone-based fundus imaging: applications and adapters].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2022
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Clinically useful smartphone ophthalmic imaging techniques.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Review
  11. Telemedicine in ophthalmology in view of the emerging COVID-19 outbreak.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Review
  12. Review
  13. Article
  14. Article
  15. Advances in retinopathy of prematurity imaging.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tapan P PatelDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA.
Michael T AabergDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA.
Yannis M PaulusDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA.
Philip LieuDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA.
Vaidehi S DedaniaDepartment of Ophthalmology, New York University School of Medicine, New York, NY, USA.
Cynthia X QianDepartment of Ophthalmology, University of Montreal, Montreal, Canada.
Cagri G BesirliDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA.
Todd MargolisDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Daniel A FletcherDepartment of Bioengineering and Biophysics Program, University of California, Berkeley, CA, USA.
Tyson N KimDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA. tyson.kim@ucsf.edu.ORCID http://orcid.org/0000-0002-5275-6614

Funding

Michigan Vision Clinician Scientist Development ProgramK12EY022299 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Abigail Fahim, DAVID N ZACKS · 2013 to 2026
$6.3M
Real-time In Vivo Visualization of the Molecular Processes in Choroidal NeovascularizationK08EY027458 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PAULUS, YANNIS MANTAS · 2018 to 2021
$898k
Knights Templar Eye Foundation Career StarterNEI NIH HHS 1K08EY027458NEI NIH HHS K08 EY027458NEI NIH HHS K12 EY022299
6 · The paper itself

Abstract

backgroundInadequate screening of treatment-warranted retinopathy of prematurity (ROP) can lead to devastating visual outcomes. Especially in resource-poor communities, the use of an affordable, portable, and easy to use smartphone-based non-contact fundus photography device may prove useful for screening for high-risk ROP. This study evaluates the feasibility of screening for high-risk ROP using a novel smartphone-based fundus photography device, RetinaScope.

methodsRetinal images were obtained using RetinaScope on a cohort of prematurely born infants during routine examinations for ROP. Images were reviewed by two masked graders who determined the image quality, the presence or absence of plus disease, and whether there was retinopathy that met predefined criteria for referral. The agreement between image-based assessments was compared to the gold standard indirect ophthalmoscopic assessment.

resultsFifty-four eyes of 27 infants were included. A wide-field fundus photograph was obtained using RetinaScope. Image quality was acceptable or excellent in 98% and 95% of cases. There was substantial agreement between the gold standard and photographic assessment of presence or absence of plus disease (Cohen's κ = 0.85). Intergrader agreement on the presence of any retinopathy in photographs was also high (κ = 0.92).

conclusionsRetinaScope can capture digital retinal photographs of prematurely born infants with good image quality for grading of plus disease.

Indexed as

Diagnostic Techniques, OphthalmologicalSmartphoneFemaleGestational AgeHumansInfant, NewbornMaleNeonatal ScreeningPhotographyProspective StudiesReproducibility of ResultsRetinopathy of PrematurityTelemedicineFundus photographyPlus diseaseRetinopathy of prematuritySmartphoneTelemedicine

Identifiers

PMID31501929
PMCPMC6824990

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.