Evidence map›Paper›PMID 31501885›Full record

ArticleBioinformatics (Oxford, England)2020

BioBERT: a pre-trained biomedical language representation model for biomedical text mining.

Jinhyuk Lee, Wonjin Yoon, Sungdong Kim, Donghyeon Kim, Sunkyu Kim, Chan Ho So, Jaewoo Kang

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,778 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,778citing papers in PubMed, 3 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,778 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jinhyuk LeeDepartment of Computer Science and Engineering, Korea University, Seoul 02841, Korea.
Wonjin YoonDepartment of Computer Science and Engineering, Korea University, Seoul 02841, Korea.
Sungdong KimClova AI Research, Naver Corp, Seong-Nam 13561, Korea.
Donghyeon KimDepartment of Computer Science and Engineering, Korea University, Seoul 02841, Korea.
Sunkyu KimDepartment of Computer Science and Engineering, Korea University, Seoul 02841, Korea.
Chan Ho SoInterdisciplinary Graduate Program in Bioinformatics, Korea University, Seoul 02841, Korea.
Jaewoo KangDepartment of Computer Science and Engineering, Korea University, Seoul 02841, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

motivationBiomedical text mining is becoming increasingly important as the number of biomedical documents rapidly grows. With the progress in natural language processing (NLP), extracting valuable information from biomedical literature has gained popularity among researchers, and deep learning has boosted the development of effective biomedical text mining models. However, directly applying the advancements in NLP to biomedical text mining often yields unsatisfactory results due to a word distribution shift from general domain corpora to biomedical corpora. In this article, we investigate how the recently introduced pre-trained language model BERT can be adapted for biomedical corpora.

resultsWe introduce BioBERT (Bidirectional Encoder Representations from Transformers for Biomedical Text Mining), which is a domain-specific language representation model pre-trained on large-scale biomedical corpora. With almost the same architecture across tasks, BioBERT largely outperforms BERT and previous state-of-the-art models in a variety of biomedical text mining tasks when pre-trained on biomedical corpora. While BERT obtains performance comparable to that of previous state-of-the-art models, BioBERT significantly outperforms them on the following three representative biomedical text mining tasks: biomedical named entity recognition (0.62% F1 score improvement), biomedical relation extraction (2.80% F1 score improvement) and biomedical question answering (12.24% MRR improvement). Our analysis results show that pre-training BERT on biomedical corpora helps it to understand complex biomedical texts. AVAILABILITY AND IMPLEMENTATION: We make the pre-trained weights of BioBERT freely available at https://github.com/naver/biobert-pretrained, and the source code for fine-tuning BioBERT available at https://github.com/dmis-lab/biobert.

Indexed as

Data MiningNatural Language ProcessingLanguageSoftware

Identifiers

PMID31501885
PMCPMC7703786

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.