ArticleAesthetic surgery journal2020
Optimizing Breast Pocket Irrigation: The Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Era.
Article in Aesthetic surgery journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Incidental Bystander or Essential Culprit: A Systematic Review of Bacterial Significance in the Pathogenesis of Breast Implant-Associated Anaplastic Large Cell Lymphoma.International journal of molecular sciences · 2023Pooled it
- Ensuring Equal Implantation Conditions on Both Sides During Breast Augmentation: Effective Decontamination of Implantation Funnels.Aesthetic plastic surgery · 2025Article
- A review of advancements in antiseptics for wound care in diabetic and non-diabetic patients.Journal of diabetes and metabolic disorders · 2025Review
- Have We Really Shifted to an Evidence-Based Practice? A Qualitative Analysis of Primary Breast Augmentation.Eplasty · 2024Article
- A prospective randomized clinical trial to assess antibiotic pocket irrigation on tissue expander breast reconstruction.Microbiology spectrum · 2023Article
- The Case Against Betadine Irrigation of Breast Implant Pockets.Aesthetic plastic surgery · 2023Article
- The Role of Microorganisms in the Development of Breast Implant-Associated Anaplastic Large Cell Lymphoma.Pathogens (Basel, Switzerland) · 2023Review
- Variation in the use of infection control measures and infection-related revision incidence after breast implant surgery in the Netherlands.JPRAS open · 2022Article
- Comparison of Breast Reconstruction Outcomes Using Oxychlorosene versus Triple Antibiotic Solution for Pocket Irrigation.Plastic and reconstructive surgery. Global open · 2022Article
- In Vitro Evaluation of Common Antimicrobial Solutions Used for Breast Implant Soaking and Breast Pocket Irrigation-Part 2: Efficacy Against Biofilm-Associated Bacteria.Aesthetic surgery journal · 2021Article
- In Vitro Evaluation of Common Antimicrobial Solutions Used for Breast Implant Soaking and Breast Pocket Irrigation-Part 1: Efficacy Against Planktonic Bacteria.Aesthetic surgery journal · 2021Article
- Revision Breast Augmentation.Seminars in plastic surgery · 2021Review
- Current Progress in Breast Implant-Associated Anaplastic Large Cell Lymphoma.Frontiers in oncology · 2021Review
- A Rebuttal of Antibiotic Irrigation as a Method to Reduce Risk of Capsular Contracture and Breast Implant-Associated Anaplastic Large-Cell Lymphoma.Annals of plastic surgery · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSpecific antimicrobial breast pocket irrigations have been proven over the past 20 years to reduce the incidence of capsular contracture by a factor of 10, and the emergence of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) and its link to bacteria/technique has created renewed interest in different antimicrobial breast pocket preparation agents. Our previous studies have identified that both Betadine-containing and non-Betadine-containing antimicrobial irrigations provide excellent broad-spectrum bacterial coverage. The current science of BIA-ALCL has implicated the Gram-negative microbiome as a key in pathogenesis.
objectivesThe aim of this study was to revisit the antimicrobial effectiveness of clinically utilized Betadine and non-Betadine solutions, along with other antimicrobial agents that have not yet been tested, against multiple organisms, including additional common Gram-negative bacteria associated with chronic breast implant infections/inflammation.
methodsCurrent and new antimicrobial breast irrigations were tested via standard techniques for bactericidal activity against multiple Gram-positive and Gram-negative strains. Test results are detailed and clinical recommendations for current antimicrobial irrigations are provided.
resultsBetadine-containing irrigations were found to be superior according to the testing performed.
conclusionsThere are quite few misconceptions with regard to antimicrobial breast pocket irrigation. These are discussed and final evidence-based recommendations for practice are given.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.