Evidence map›Paper›PMID 31501799›Full record

ArticleInvestigative and clinical urology2019

A novel human cadaver model to investigate a retrourethral transobturator male sling procedure.

Sean F Mungovan, William I Jaffe, Petra L Graham, Manish I Patel, Jaspreet S Sandhu

Open access · diamondAbstract read
In one paragraph

Article in Investigative and clinical urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Sean F MungovanWestmead Private Physiotherapy Services, Westmead Private Hospital Sydney, Sydney, Australia.
William I JaffeDivision of Urology, Department of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA.
Petra L GrahamCentre for Economic Impacts of Genomic Medicine (GenIMPACT), Macquarie University, Sydney, Australia.
Manish I PatelDepartment of Urology, Westmead Hospital, Sydney, Australia.
Jaspreet S SandhuUrology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.ORCID 0000-0001-6590-4041
Macquarie University · AUMemorial Sloan Kettering Cancer Center · USThe University of Sydney · AUUniversity of Pennsylvania Health System · USWestmead Hospital · AU

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Purpose: To develop a cadaver model for the assessment of a male transobturator male sling (retrourethral transobturator sling [RTS], AdVance™; Boston Scientific, USA) to investigate its effect on a simulated abdominal and retrograde leak point pressures (ALPP, RLPP) and the urethral pressure profile (UPP). Materials and Methods: Three fresh frozen human male cadaver specimens were obtained. A suprapubic tube was inserted into the bladder and connected to a digital manometer to measure bladder pressure. Manual suprapubic pressure was then applied to generate an increase in intraabdominal pressure and measure a simulated ALPP. Subsequent measurements of RLPP and UPP were recorded. All measurements were undertaken prior to and following insertion of a RTS. Results: The placement of the RTS consistently increased the simulated ALPP for all three cadaver specimens when compared to baseline measures. No leaks occurred at simulated ALPP's of 170 cm H Conclusions: A model using fresh unfixed cadavers that incorporates a simulated measurement of ALPP is feasible for male stress urinary incontinence surgical intervention investigations.

Indexed as

Suburethral SlingsAgedCadaverHumansMaleMiddle AgedUrethraUrinary Incontinence, StressUrologic Surgical Procedures, MaleCadaverMaleSuburethral slingsUrinary bladderUrinary incontinence

Identifiers

PMID31501799
PMCPMC6722399
OpenAlexW2949631696

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.