ArticleJournal of dental anesthesia and pain medicine2019
Effects site concentrations of propofol using target-controlled infusion in dental treatment under deep sedation among different intellectual disability types.
Article in Journal of dental anesthesia and pain medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Outpatient intravenous sedation for dental treatment in patients with special health care needs: a five-year retrospective study in Venezuela.Frontiers in oral health · 2026Article
- Analysis of sedation and general anesthesia in patients with special needs in dentistry using the Korean healthcare big data.Journal of dental anesthesia and pain medicine · 2022Article
- Comparison of the effects of target-controlled infusion-remifentanil/midazolam and manual fentanyl/midazolam administration on patient parameters in dental procedures.Journal of dental anesthesia and pain medicine · 2022Article
- Analysis of behavioral management for dental treatment in patients with dementia using the Korean National Health Insurance data.Journal of dental anesthesia and pain medicine · 2021Article
- Effectiveness and Safety of Intravenous Sedation with Propofol in Non-Operating Room Anesthesia (NORA) for Dental Treatment in Uncooperative Paediatric Patients.Children (Basel, Switzerland) · 2021Article
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Authors and funding
3 authors.
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Abstract
backgroundWe aimed to assess the dose needed to achieve the propofol effect-site concentration using target-controlled infusion in intellectually disabled patients and to detail the most effective method for achieving a safe level of consciousness without hemodynamic changes as well as detail any resulting adverse effects.
methodsWe performed a retrospective review of sedation service records of 138 intellectually disabled patients (51, mental retardation; 36, autism; 30, brain lesion, 12 genetic diseases, 9 dementia) aged over 15 years and weighing over 30 kg. These patients had received propofol via target-controlled infusion in the special care dental clinic of Seoul National University Dental Hospital from May 2008 to September 2018 for restorative treatment (112), minor surgery (13), prosthodontics (7), periodontics treatment (5), and implant (1).
resultsFor all groups, the duration of dental treatments was 43 ± 18 minutes, total sedation time was 73 ± 23 minutes, and total BIS values was 57 ± 12. The propofol maintenance dosage values for each group were: mental retardation, 3 ± 0.5 (2-4) µg/ml; autism, 3.1 ± 0.7 (2-5) µg/ml; brain lesion, 2.8 ± 0.7 (1.5-5) µg/ml; genetic disease, 2.9 ± 0.9 (1-4) µg/ml; and dementia 2.3 ± 0.7 (1-3.4) µg/ml.
conclusionsThe dementia group needed a lower dosage to reach a safe, effective propofol effect-site concentration than the other groups. Since there were no complications, deep sedation is a great alternative to general anesthesia for dental treatment of intellectually disabled patients.
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