Evidence map›Paper›PMID 31501771›Full record

ReviewScience advances2019

The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium.

John S Satterlee, Lisa H Chadwick, Frederick L Tyson, Kim McAllister, Jill Beaver, Linda Birnbaum, Nora D Volkow, Elizabeth L Wilder, James M Anderson, Ananda L Roy

Abstract readReview
In one paragraph

Review in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
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  8. Brain region and cell specificity ofWorld journal of psychiatry · 2025
    Article
  9. Article
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  11. Review
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  14. Review
  15. Mechanism of Histone Arginine Methylation Dynamic Change in Cellular Stress.International journal of molecular sciences · 2024
    Article
  16. Review
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

John S SatterleeDivision of Neuroscience and Behavior, National Institutes of Health (NIH), 6001 Executive Blvd., Bethesda, MD 20892, USA.ORCID 0000-0002-3396-1014
Lisa H ChadwickNational Institute on Drug Abuse, NIH, 6001 Executive Blvd., Bethesda, MD 20892, USA.ORCID 0000-0002-2539-1306
Frederick L TysonNational Institute of Environmental Health Sciences, NIH, 111 TW Alexander Dr., Durham, NC 27709, USA.
Kim McAllisterNational Institute of Environmental Health Sciences, NIH, 111 TW Alexander Dr., Durham, NC 27709, USA.
Jill BeaverOffice of Strategic Coordination, Office of the Director, NIH, 6001 Executive Blvd., Bethesda, MD 20892, USA.
Linda BirnbaumNational Institute of Environmental Health Sciences, NIH, 111 TW Alexander Dr., Durham, NC 27709, USA.ORCID 0000-0001-5429-5658
Nora D VolkowNational Institute on Drug Abuse, NIH, 6001 Executive Blvd., Bethesda, MD 20892, USA.ORCID 0000-0001-6668-0908
Elizabeth L WilderOffice of Strategic Coordination, Office of the Director, NIH, 6001 Executive Blvd., Bethesda, MD 20892, USA.ORCID 0000-0002-8741-8041
James M AndersonDivision of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, NIH, 1 Center Dr., Bethesda, MD 20892, USA.ORCID 0000-0003-2765-7996
Ananda L RoyOffice of Strategic Coordination, Office of the Director, NIH, 6001 Executive Blvd., Bethesda, MD 20892, USA.ORCID 0000-0002-0686-5748

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse human diseases. Here, we comment on the outcomes from this program: the scientific contributions made possible by a consortium approach and the challenges, benefits, and lessons learned from this group science effort.

Indexed as

Epigenesis, GeneticEpigenomicsFinancial ManagementNational Institutes of Health (U.S.)HumansUnited States

Identifiers

PMID31501771
PMCPMC6719411

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.