ArticleNature medicine2019
Sensory feedback restoration in leg amputees improves walking speed, metabolic cost and phantom pain.
3 registry-linked trialsAbstract read
In one paragraph
Article in Nature medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 118 papers, 5 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed, 5 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Enhancing Functional and Cognitive Performances in People With Amputation and Peripheral Neuropathy Through the Restoration of Sensory Feedback in Real World and Virtual Reality Environments
Peripheral Nerve and Spinal Cord Stimulation in Patients With Pain Syndrome as a Result of Lower Limb Amputation in Order to Relieve Pain Syndrome and Develop Phantom Pain Biomarkers
Neuroprosthetic Device for Improving Issues Caused by Diabetic Neuropathy With Specifically Designed Neural Stimulation
Who cites it
118 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Therapeutic benefits of lower limb prostheses: a systematic review.Journal of neuroengineering and rehabilitation · 2023Pooled it
- A review of user needs to drive the development of lower limb prostheses.Journal of neuroengineering and rehabilitation · 2022Pooled it
- Artificial referred sensation in upper and lower limb prosthesis users: a systematic review.Journal of neural engineering · 2022Pooled it
- Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics.Frontiers in bioengineering and biotechnology · 2021Pooled it
- Biofeedback Systems for Gait Rehabilitation of Individuals with Lower-Limb Amputation: A Systematic Review.Sensors (Basel, Switzerland) · 2020Pooled it
- Trial
- Neural Interfaces for Bidirectional Sensory Restoration in Limb Prostheses: Current Evidence and Clinical Translation.Journal of clinical medicine · 2026Review
- Trends in neuroprosthetic technologies to restore sensations.Biomedical engineering letters · 2026Review
- logLIRA: a method for reliable suppression of electrical stimulation artifacts enabling short-latency neural response recovery.Journal of neural engineering · 2026Article
- The optimization of neuroprosthetic interfaces relying on biophysical and surrogate digital twins.npj biomedical innovations · 2026Review
- Mechanomedicine.Nature reviews bioengineering · 2026Article
- Edge AI-Based Gait-Phase Detection for Closed-Loop Neuromodulation in SCI Mice.Sensors (Basel, Switzerland) · 2026Article
- Decoding phantom limb movements from intraneural recordings.Nature communications · 2026Article
- On the reliability of non-hermetically encapsulated ceramic printed circuit boards as bridging elements in neural implants.Frontiers in neuroscience · 2026Article
- A Bioinspired Perceptual Sensor for Spatiotemporal Decoding of Haptic and Pain Stimuli in Prostheses.Cyborg and bionic systems (Washington, D.C.) · 2026Article
- Development and assessment of vibrotactile feedback from the embedded sensors of a microprocessor-controlled knee prosthesis.Journal of neuroengineering and rehabilitation · 2025Article
- Adhesive nonfibrotic bioelectronic interfaces on diverse peripheral nerves for long-term functional neuromodulation.Science advances · 2025Article
- Characterizing spinal reflexes evoked by sensory spinal cord stimulation in people with lower-limb amputation.Journal of neuroengineering and rehabilitation · 2025Article
- Impact of Long-Term Home and Community Use of a Lower Limb Sensory Neuroprosthesis.Research square · 2025Article
- Haptic Feedback Systems for Lower-Limb Prosthetic Applications: A Review of System Design, User Experience, and Clinical Insights.Bioengineering (Basel, Switzerland) · 2025Review
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Francesco Maria Petrini *Department of Health Sciences and Technology, Institute of Robotics and Intelligent Systems, Swiss Federal Institute of Technology Zürich, Zürich, Switzerland.
Marko Bumbasirevic *Orthopaedic Surgery Department, School of Medicine University of Belgrade, Belgrade, Serbia.
Giacomo Valle *Bertarelli Foundation Chair in Translational Neuroengineering, Centre for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-2637-8007
Vladimir IlicFaculty of Sport and Physical Education, School of Medicine, University of Belgrade, Belgrade, Serbia.
Pavle MijovićmBrainTrain d.o.o., Belgrade, Serbia.
Paul ČvančaraLaboratory for Biomedical Microtechnology, Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany.
Federica BarberiSensArs Neuroprosthetics, Lausanne, Switzerland.
Natalija KaticInstitute Mihajlo Pupin, Belgrade, Serbia.
Dario BortolottiSensArs Neuroprosthetics, Lausanne, Switzerland.
David AndreuInria, University of Montpellier, Montpellier, France.
Knut LechlerÖssur, Reykjavik, Iceland.ORCID http://orcid.org/0000-0002-9337-6829
Aleksandar LesicOrthopaedic Surgery Department, School of Medicine University of Belgrade, Belgrade, Serbia.
Sanja MazicInstitute of Medical Physiology, School of Medicine, University of Belgrade, Belgrade, Serbia.
Bogdan MijovićmBrainTrain d.o.o., Belgrade, Serbia.
David GuiraudInria, University of Montpellier, Montpellier, France.
Thomas StieglitzLaboratory for Biomedical Microtechnology, Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-7349-4254
Asgeir AlexanderssonÖssur, Reykjavik, Iceland.ORCID http://orcid.org/0000-0003-1723-499X
Silvestro MiceraBertarelli Foundation Chair in Translational Neuroengineering, Centre for Neuroprosthetics and Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Stanisa RaspopovicDepartment of Health Sciences and Technology, Institute of Robotics and Intelligent Systems, Swiss Federal Institute of Technology Zürich, Zürich, Switzerland. stanisa.raspopovic@hest.ethz.ch.ORCID http://orcid.org/0000-0003-0567-9051
Funding
EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 754497EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 759998Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 176006
Abstract
Conventional leg prostheses do not convey sensory information about motion or interaction with the ground to above-knee amputees, thereby reducing confidence and walking speed in the users that is associated with high mental and physical fatigue
Indexed as
Artificial LimbsAdultAmputeesBiomechanical PhenomenaFeedback, SensoryHumansKneeMaleMiddle AgedPhantom LimbWalking Speed
Identifiers
PMID
31501600What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.