ArticleScientific reports2019
A transcriptome-based phylogenetic study of hard ticks (Ixodidae).
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- The complete mitogenome of Hyalomma anatolicum: novel insights into the phylogenetics of Hyalomma.Parasitology research · 2025Article
- Characterization of the complete mitochondrial genome of Monticola rufiventris and phylogenetic implications.Scientific reports · 2025Article
- Improving distribution models of sparsely documented disease vectors by incorporating information on related species via joint modeling.Ecography · 2025Article
- Article
- Genetic and genomic variability ofISME communications · 2025Article
- Hard Ticks as Vectors: The Emerging Threat of Tick-Borne Diseases in India.Pathogens (Basel, Switzerland) · 2024Review
- Endogenous Viral Elements in Ixodid Tick Genomes.Viruses · 2023Article
- Molecular-phylogenetic analyses of Ixodes species from South Africa suggest an African origin of bird-associated exophilic ticks (subgenus Trichotoixodes).Parasites & vectors · 2023Article
- Exploring Evolutionary Relationships within Neodermata Using Putative Orthologous Groups of Proteins, with Emphasis on Peptidases.Tropical medicine and infectious disease · 2023Article
- Development and field evaluation of PCR assays based on minimum lengthFrontiers in veterinary science · 2023Article
- Integrated Jingmenvirus Polymerase Gene inViruses · 2022Article
- A remarkable assemblage of ticks from mid-Cretaceous Burmese amber.Parasitology · 2022Article
- Necrotic reshaping of the glioma microenvironment drives disease progression.Acta neuropathologica · 2022Review
- Taxonomic Sampling and Rare Genomic Changes Overcome Long-Branch Attraction in the Phylogenetic Placement of Pseudoscorpions.Molecular biology and evolution · 2021Article
- The complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2021Article
- Perpetuation of Borreliae.Current issues in molecular biology · 2021Article
- Tick species from Africa by migratory birds: a 3-year study in Italy.Experimental & applied acarology · 2021Review
- De novo assembly and analysis of the transcriptome of the Dermacentor marginatus genes differentially expressed after blood-feeding and long-term starvation.Parasites & vectors · 2020Article
- Quantitative Visions of Reality at the Tick-Host Interface: Biochemistry, Genomics, Proteomics, and Transcriptomics as Measures of Complete Inventories of the Tick Sialoverse.Frontiers in cellular and infection microbiology · 2020Review
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10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hard ticks are widely distributed across temperate regions, show strong variation in host associations, and are potential vectors of a diversity of medically important zoonoses, such as Lyme disease. To address unresolved issues with respect to the evolutionary relationships among certain species or genera, we produced novel RNA-Seq data sets for nine different Ixodes species. We combined this new data with 18 data sets obtained from public databases, both for Ixodes and non-Ixodes hard tick species, using soft ticks as an outgroup. We assembled transcriptomes (for 27 species in total), predicted coding sequences and identified single copy orthologues (SCO). Using Maximum-likelihood and Bayesian frameworks, we reconstructed a hard tick phylogeny for the nuclear genome. We also obtained a mitochondrial DNA-based phylogeny using published genome sequences and mitochondrial sequences derived from the new transcriptomes. Our results confirm previous studies showing that the Ixodes genus is monophyletic and clarify the relationships among Ixodes sub-genera. This work provides a baseline for studying the evolutionary history of ticks: we indeed found an unexpected acceleration of substitutions for mitochondrial sequences of Prostriata, and for nuclear and mitochondrial genes of two species of Rhipicephalus, which we relate with patterns of genome architecture and changes of life-cycle, respectively.
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