ArticleScientific reports2019
The association of gut microbiota characteristics in Malawian infants with growth and inflammation.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review of associations between gut microbiome composition and stunting in under-five children.NPJ biofilms and microbiomes · 2024Pooled it
- Diet, adiposity, and the gut microbiota from infancy to adolescence: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Pooled it
- Associations between maternal obesity and offspring gut microbiome in the first year of life.Pediatric obesity · 2022Trial
- Factors Associated With the Microbiome in Moderate-Late Preterm Babies: A Cohort Study From the DIAMOND Randomized Controlled Trial.Frontiers in cellular and infection microbiology · 2021Trial
- Infant gut microbiota characteristics generally do not modify effects of lipid-based nutrient supplementation on growth or inflammation: secondary analysis of a randomized controlled trial in Malawi.Scientific reports · 2020Trial
- Trial
- Early-life microbiome trajectories as biomarkers to predict health outcomes.Microbiome research reports · 2026Review
- Rurality and relative poverty drive acquisition of a stable and diverse gut microbiome in early childhood in a non-industrialized setting.Scientific reports · 2025Article
- Maternal characteristics are associated with human milk anti-inflammatory proteins in two populations.Scientific reports · 2024Article
- Rurality and relative poverty drive acquisition of a stable and diverse gut microbiome in early childhood in a non-industrialized setting.Research square · 2024Article
- Complementary Feeding: Tradition, Innovation and Pitfalls.Nutrients · 2024Review
- Associations of Plastic Bottle Exposure with Infant Growth, Fecal Microbiota, and Short-Chain Fatty Acids.Microorganisms · 2023Article
- A Scoping Review Evaluating the Current State of Gut Microbiota Research in Africa.Microorganisms · 2023Article
- Composition of the intestinal microbiota of infant rhesus macaques at different ages before and after weaning.Heliyon · 2023Article
- The gut microbiome and early-life growth in a population with high prevalence of stunting.Nature communications · 2023Article
- Microbial associations and transfers across the One Health Triad effects on human and animal adiposity and temperament: a protocol for an observational pilot study.Frontiers in public health · 2023Article
- Robust variation in infant gut microbiome assembly across a spectrum of lifestyles.Science (New York, N.Y.) · 2022Article
- Different gut microbiota in U.S. formula-fed infants consuming a meat vs. dairy-based complementary foods: A randomized controlled trial.Frontiers in nutrition · 2022Article
- Associations of human milk oligosaccharides and bioactive proteins with infant growth and development among Malawian mother-infant dyads.The American journal of clinical nutrition · 2021Article
- Differences in immune status and fecal SCFA between Indonesian stunted children and children with normal nutritional status.PloS one · 2021Observational
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We tested the hypotheses that a more mature or diverse gut microbiota will be positively associated with infant growth and inversely associated with inflammation. We characterized gut microbiota from the stool samples of Malawian infants at 6 mo (n = 527), 12 mo (n = 632) and 18 mo (n = 629) of age. Microbiota diversity and maturity measurements were based on Shannon diversity index and microbiota for age Z-score (MAZ), respectively. Growth was calculated as change in Z-scores for weight-for-age (WAZ), length-for-age (LAZ) and head circumference-for-age (HCZ) from 6 to 12 mo and 12 to 18 mo. Biomarkers of inflammation (alpha-1-acid glycoprotein (AGP) and C-reactive protein (CRP)) were measured at 6 and 18 mo. Multivariable models were used to assess the association of each independent variable with each outcome. Microbiota diversity and maturity were related to growth in weight from 6 to 12 mo, but not to growth in length or head circumference or to growth from 12 to 18 mo. Microbiota diversity and maturity may also be linked to inflammation, but findings were inconsistent.
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Registered trials
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