ArticleScientific reports2019
White matter microstructure mediates the association between physical fitness and cognition in healthy, young adults.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diurnal variation in variables related to cognitive performance: a systematic review.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- Associations of cardiorespiratory fitness and exercise with brain white matter in healthy adults: A systematic review and meta-analysis.Brain imaging and behavior · 2022Pooled it
- Effect of physical exercise on white matter microstructure in chemotherapy-treated breast cancer patients: a randomized controlled trial (PAM study).Brain imaging and behavior · 2025Trial
- The relationship between white matter microstructure, cardiovascular fitness, gross motor skills, and neurocognitive functioning in children.Journal of neuroscience research · 2021Trial
- The association between motor coordination, behavior, cognition and brain structure in children: an ABCD study.European child & adolescent psychiatry · 2026Article
- Time course of functional and structural brain network changes after mild traumatic brain injury.Brain communications · 2026Article
- Effects of Aging, Estimated Fitness, and Cerebrovascular Status on White Matter Microstructural Health.Human brain mapping · 2025Article
- Associations between cardiorespiratory fitness and executive function in Chinese adolescents.Scientific reports · 2024Article
- Exercise Reshapes the Brain: Molecular, Cellular, and Structural Changes Associated with Cognitive Improvements.Molecular neurobiology · 2023Review
- Risk factors for neurocognitive impairment and the relation with structural brain abnormality in children and young adults with severe chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2023Article
- Physical fitness, cognition, and structural network efficiency of brain connections across the lifespan.Neuropsychologia · 2023Article
- Neurite dispersion and density mediates the relationship between cardiorespiratory fitness and cognition in healthy younger adults.Neuropsychologia · 2022Article
- Association of brain white matter microstructure with cognitive performance in major depressive disorder and healthy controls: a diffusion-tensor imaging study.Molecular psychiatry · 2022Article
- Exercise engagement drives changes in cognition and cardiorespiratory fitness after 8 weeks of aerobic training in sedentary aging adults at risk of cognitive decline.Frontiers in rehabilitation sciences · 2022Article
- Age-Related Trajectories of Brain Structure-Function Coupling in Female Roller Derby Athletes.Brain sciences · 2021Article
- Evidence for exercise-related plasticity in functional and structural neural network connectivity.Neuroscience and biobehavioral reviews · 2021Review
- Cardiovascular Endurance Modifies the Link between Subjective Sleep Quality and Entorhinal Cortex Thickness in Younger Adults.Medicine and science in sports and exercise · 2021Article
- Influence of Aerobic Fitness on White Matter Integrity and Inhibitory Control in Early Adulthood: A 9-Week Exercise Intervention.Brain sciences · 2021Article
- Elevated body weight modulates subcortical volume change and associated clinical response following electroconvulsive therapy.Journal of psychiatry & neuroscience : JPN · 2021Article
- [Sport and physical exercise in unipolar depression : Prevention, therapy, and neurobiological mechanisms of action].Der Nervenarzt · 2021Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
We aimed to extend our knowledge on the relationship between physical fitness (PF) and both white matter microstructure and cognition through in-depth investigation of various cognitive domains while accounting for potentially relevant nuisance covariates in a well-powered sample. To this end, associations between walking endurance, diffusion-tensor-imaging (DTI) based measures of fractional anisotropy (FA) within brain white matter and cognitive measures included in the NIH Toolbox Cognition Battery were investigated in a sample of n = 1206 healthy, young adults (mean age = 28.8; 45.5% male) as part of the human connectome project. Higher levels of endurance were associated with widespread higher FA (p
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.