ArticleNature communications2019
Zebrafish behavioural profiling identifies GABA and serotonin receptor ligands related to sedation and paradoxical excitation.
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In one paragraph
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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0cells of the map it votes in
35citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
What it found
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Who cites it
35 citing papers in PubMed, 58 citations in OpenAlex.
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- Multibehavioral Phenotyping in Early-Life-Stage Zebrafish for Identifying Disruptors of Nonassociative Learning.Environmental health perspectives · 2026Article
- Volatile anaesthetics modulate voltage-gated sodium channel function at a site directly linked to channel gating.Nature communications · 2026Article
- In Vivo Characterization of Synthetic Cannabidiol Analogs for Seizure Suppression in Zebrafish.ACS chemical neuroscience · 2026Article
- Versatile CRISPR-Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Benzodiazepines at the crossroads: navigating therapeutic promise and perils of misuse.Annals of general psychiatry · 2026Review
- High-throughput multi-camera array microscope platform for automated 3D behavioral analysis of swimming zebrafish larvae.Communications biology · 2026Article
- Fecal microbiota transplantation and Akkermansia muciniphila restore neurodevelopment and behavior via the gut-brain axis in autism-like zebrafish.The ISME journal · 2026Article
- Identification of Neuroactive Chemicals in Crude Oil-Derived Water-Accommodated Fractions.Environmental science & technology · 2026Article
- Persistent and Dose-Dependent Neural and Metabolic Gene Expression Changes Induced by Transient Citalopram Exposure in Zebrafish Embryos.International journal of molecular sciences · 2025Article
- High-throughput multi-camera array microscope platform for automated 3D behavioral analysis of swimming zebrafish larvae.bioRxiv : the preprint server for biology · 2025Article
- Disrupted diencephalon development and neuropeptidergic pathways in zebrafish with autism-risk mutations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Effects of progestogen neurosteroids on locomotor activity in zebrafish embryos and larvae.Fish physiology and biochemistry · 2025Article
- Behavioral Profiling in Zebrafish Identifies Insecticide-Related Compounds.Journal of agricultural and food chemistry · 2025Article
- Article
- High throughput machine learning pipeline to characterize larval zebrafish motor behavior.PloS one · 2025Article
- Across preclinical and clinical platforms, approved and investigational psychiatric drugs share pathways and associate with similar molecular functions.Frontiers in drug discovery · 2025Article
- A Multimodal, In Vivo Approach for Assessing Structurally and Phenotypically Related Neuroactive Molecules.ACS chemical neuroscience · 2024Article
- Deep phenotypic profiling of neuroactive drugs in larval zebrafish.Nature communications · 2024Article
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 1 country.
Matthew N McCarrollInstitute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94143, USA.
Leo GendelevInstitute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94143, USA.
Reid KinserInstitute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94143, USA.
Jack TaylorInstitute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94143, USA.ORCID http://orcid.org/0000-0002-6431-9956
Giancarlo BruniCardiovascular Research Center and Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.ORCID http://orcid.org/0000-0003-2850-4633
Douglas Myers-TurnbullInstitute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94143, USA.ORCID http://orcid.org/0000-0003-3610-4808
Cole HelsellInstitute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94143, USA.
Amanda CarbajalDepartment of Biology, San Francisco State University, San Francisco, CA, USA.
Capria RinaldiInstitute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94143, USA.
Hye Jin KangDepartment of Pharmacology and NIMH Psychoactive Drug Screening Program, University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27759, USA.
Jung Ho GongDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.
Jason K SelloDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.
Susumu TomitaDepartment of Cellular and Molecular Physiology, Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 06510, USA.
Randall T PetersonCardiovascular Research Center and Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
Michael J KeiserInstitute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94143, USA. keiser@keiserlab.org.ORCID http://orcid.org/0000-0002-1240-2192
David KokelInstitute for Neurodegenerative Diseases, University of California, San Francisco, CA, 94143, USA. david.kokel@ucsf.edu.
University of California, San Francisco · USBrown University · USHarvard University · USSan Francisco State University · USUniversity of North Carolina at Chapel Hill · USYale University · US
Funding
SFSU MBRS - RISER25GM059298 · NIGMS · SAN FRANCISCO STATE UNIVERSITY · PI BAIRD, TEASTER T, BAYLISS, FRANK T · 1999 to 2021
$21.0MSTRUCTURAL BIOLOGY TRAINING PROGRAMT32GM008284 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KORTEMME, TANJA · 1988 to 2022
$10.1MBMI Bioinformatics Training GrantsT32GM067547 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HERNANDEZ, RYAN D. · 2003 to 2022
$6.6MIntegrative Program in Complex Biological System (ipCBS)T32EB009383 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARSHALL, WALLACE, WEINER, ORION D · 2009 to 2022
$3.2MMechanisms for synaptic localization of ionotropic GABA receptors in the brainR01MH115705 · NIMH · YALE UNIVERSITY · PI TOMITA, SUSUMU · 2018 to 2022
$2.1MBehavior-based chemical screening for GABAergic and startle modifying drugsR01AA022583 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KOKEL, DAVID · 2013 to 2017
$1.6MIdentify functional modulators of ionotropic neurotransmitter receptors in brainU01MH104984 · NIMH · YALE UNIVERSITY · PI TOMITA, SUSUMU · 2014 to 2016
$1.0MNIAAA NIH HHS R01 AA022583NIBIB NIH HHS T32 EB009383NIGMS NIH HHS R25 GM059298NIGMS NIH HHS T32 GM008284NIMH NIH HHS R01 MH115705NIMH NIH HHS U01 MH104984
Abstract
Anesthetics are generally associated with sedation, but some anesthetics can also increase brain and motor activity-a phenomenon known as paradoxical excitation. Previous studies have identified GABA
Indexed as
Behavior, AnimalProcedural SedationAnimalsLigandsNeural InhibitionNeuronsReceptors, GABA-AReceptors, SerotoninSerotonin AntagonistsZebrafishZebrafish ProteinsLigandsReceptors, GABA-AReceptors, SerotoninSerotonin AntagonistsZebrafish Proteins
Identifiers
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.