ArticleNature communications2019
Thermal cues drive plasticity of desiccation resistance in montane salamanders with implications for climate change.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 64 citations in OpenAlex.
- Embryonic thermal environments drive plasticity in gene expression.Fish physiology and biochemistry · 2025Article
- Behavioural evidence of a humidistat: a temperature-compensating mechanism of hydroregulation in spotted salamanders.The Journal of experimental biology · 2025Article
- Seasonal plasticity in the thermal sensitivity of metabolism but not water loss in a fossorial ectotherm.Oecologia · 2025Article
- A user's guide for understanding reptile and amphibian hydroregulation and climate change impacts.Conservation physiology · 2025Article
- Water Availability and Temperature as Modifiers of Evaporative Water Loss in Tropical Frogs.Integrative and comparative biology · 2024Article
- Seasonal variation of behavioural thermoregulation in a fossorial salamander (Royal Society open science · 2024Article
- Impacts of behaviour and acclimation of metabolic rate on energetics in sheltered ectotherms: a climate change perspective.Proceedings. Biological sciences · 2024Article
- Hydric physiology and ecology of a federally endangered desert lizard.Conservation physiology · 2024Article
- Behavioural hydroregulation protects against acute effects of drought in a dry-skinned ectotherm.Oecologia · 2023Article
- Identification ofPharmacogenomics and personalized medicine · 2022Article
- CENPL, ISG20L2, LSM4, MRPL3 are four novel hub genes and may serve as diagnostic and prognostic markers in breast cancer.Scientific reports · 2021Article
- Abundance of montane salamanders over an elevational gradient.Ecology and evolution · 2021Article
- Harnessing the potential of cross-protection stressor interactions for conservation: a review.Conservation physiology · 2021Article
- Article
- Inter- and intraspecific variation in juvenile metabolism and water loss among five biphasic amphibian species.Oecologia · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organisms rely upon external cues to avoid detrimental conditions during environmental change. Rapid water loss, or desiccation, is a universal threat for terrestrial plants and animals, especially under climate change, but the cues that facilitate plastic responses to avoid desiccation are unclear. We integrate acclimation experiments with gene expression analyses to identify the cues that regulate resistance to water loss at the physiological and regulatory level in a montane salamander (Plethodon metcalfi). Here we show that temperature is an important cue for developing a desiccation-resistant phenotype and might act as a reliable cue for organisms across the globe. Gene expression analyses consistently identify regulation of stem cell differentiation and embryonic development of vasculature. The temperature-sensitive blood vessel development suggests that salamanders regulate water loss through the regression and regeneration of capillary beds in the skin, indicating that tissue regeneration may be used for physiological purposes beyond replacing lost limbs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.