Evidence map›Paper›PMID 31501288›Full record

ArticleJournal of bacteriology2019

CidR and CcpA Synergistically Regulate Staphylococcus aureus

Marat R Sadykov, Ian H Windham, Todd J Widhelm, Vijaya Kumar Yajjala, Sean M Watson, Jennifer L Endres, Arissa I Bavari, Vinai C Thomas, Jeffrey L Bose, Kenneth W Bayles

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Understanding bacterial biofilms: From definition to treatment strategies.Frontiers in cellular and infection microbiology · 2023
    Pooled it
  2. Article
  3. Journal of bacteriology · 2025
    Article
  4. Review
  5. Frontiers in cellular and infection microbiology · 2023
    Article
  6. Review
  7. CcpA RegulatesAntibiotics (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Targeting the Achilles' Heel of Multidrug-ResistantInternational journal of molecular sciences · 2022
    Article
  10. Delineating the Role of theFrontiers in microbiology · 2022
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Marat R Sadykov *Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Ian H Windham *Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Todd J WidhelmDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Vijaya Kumar YajjalaDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Sean M WatsonDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Jennifer L EndresDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Arissa I BavariDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Vinai C ThomasDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID 0000-0002-7886-0727
Jeffrey L BoseDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Kenneth W BaylesDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA kbayles@unmc.edu.
University of Nebraska Medical Center · USUniversity of Kansas Medical Center · US

Funding

The S. aureus biofilm lifecycleP01AI083211 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAYLES, KENNETH W. · 2009 to 2023
$32.1M
The molecular control of bacterial programmed cell deathR01AI125589 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAYLES, KENNETH W. · 2016 to 2020
$1.9M
NIAID NIH HHS P01 AI083211NIAID NIH HHS R01 AI125589
6 · The paper itself

Abstract

The death and lysis of a subpopulation of

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsBase SequenceBiofilmsDNA-Binding ProteinsElectrophoretic Mobility Shift AssayGenes, ReporterOperonPromoter Regions, GeneticProtein BindingReal-Time Polymerase Chain ReactionRecombinant Fusion ProteinsStaphylococcus aureusTranscription, GeneticBacterial ProteinsDNA-Binding ProteinsRecombinant Fusion Proteinscarbon catabolite repressionglycolysisregulation of gene expressionStaphylococcus aureus

Identifiers

PMID31501288
PMCPMC6832070
OpenAlexW2972621509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.