Evidence map›Paper›PMID 31501265›Full record

ReviewCold Spring Harbor perspectives in medicine2019

Precise Immunodetection of PTEN Protein in Human Neoplasia.

Rafael Pulido, Janire Mingo, Ayman Gaafar, Caroline E Nunes-Xavier, Sandra Luna, Leire Torices, Javier C Angulo, José I López

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Immunohistochemistry for PTEN testing in HR +/HER2- metastatic breast cancer.Virchows Archiv : an international journal of pathology · 2025
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  11. Toward Systems Pathology for PTEN Diagnostics.Cold Spring Harbor perspectives in medicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Rafael PulidoBiocruces Bizkaia Health Research Institute, Barakaldo 48903, Spain.
Janire MingoBiocruces Bizkaia Health Research Institute, Barakaldo 48903, Spain.
Ayman GaafarDepartment of Pathology, Cruces University Hospital, Barakaldo 48903, Spain.ORCID 0000-0003-0324-2251
Caroline E Nunes-XavierBiocruces Bizkaia Health Research Institute, Barakaldo 48903, Spain.
Sandra LunaBiocruces Bizkaia Health Research Institute, Barakaldo 48903, Spain.
Leire ToricesBiocruces Bizkaia Health Research Institute, Barakaldo 48903, Spain.
Javier C AnguloDepartment of Urology, University Hospital of Getafe, Getafe, Madrid 28904, Spain.
José I LópezBiocruces Bizkaia Health Research Institute, Barakaldo 48903, Spain.
BioCruces Health research Institute · ESHospital de Cruces · ESHospital Universitario de Getafe · ESIkerbasque · ESOslo University Hospital · NOUniversity of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PTEN is a major tumor-suppressor protein whose expression and biological activity are frequently diminished in sporadic or inherited cancers.

Indexed as

MutationBiomarkers, TumorHumansImmunohistochemistryNeoplasmsPrognosisPTEN PhosphohydrolaseBiomarkers, TumorPTEN PhosphohydrolasePTEN protein, human

Identifiers

PMID31501265
PMCPMC6886455
OpenAlexW2972680580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.