Evidence map›Paper›PMID 31501250›Full record

ArticleInfection and immunity2019

Elucidation of the Interleukin 12 Production Mechanism during Intracellular Bacterial Infection in Amberjack,

Megumi Matsumoto, Taisei Kubota, Sinsuke Fujita, Kazuhiro Shiozaki, Shosei Kishida, Atsushi Yamamoto

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Expression and Immune Response Profiles in Nile Tilapia (International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Megumi MatsumotoThe United Graduate School of Agricultural Sciences, Kagoshima University, Kagoshima, Japan.
Taisei KubotaFaculty of Fisheries, Kagoshima University, Kagoshima, Japan.
Sinsuke FujitaFaculty of Fisheries, Kagoshima University, Kagoshima, Japan.
Kazuhiro ShiozakiThe United Graduate School of Agricultural Sciences, Kagoshima University, Kagoshima, Japan.
Shosei KishidaFaculty of Medicine, Kagoshima University, Kagoshima, Japan.
Atsushi YamamotoThe United Graduate School of Agricultural Sciences, Kagoshima University, Kagoshima, Japan ayam@fish.kagoshima-u.ac.jp.
Kagoshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular bacterial infections affect all vertebrates. Cultured fish are particularly vulnerable because no effective protection measures have been established since such infections emerged approximately 50 years ago. As in other vertebrates, the induction of cell-mediated immunity (CMI) plays an important role in protecting fish against infection. However, details of the mechanism of CMI induction in fish have not been clarified. In the present study, we focused on the production of interleukin 12 (IL-12), an important factor in CMI induction in fish. Using several different approaches, we investigated IL-12 regulation in amberjack (

Indexed as

NocardiaAnimalsCell LineFish DiseasesFishesGene Expression RegulationInterleukin-12LeukocytesNocardia InfectionsPromoter Regions, GeneticInterleukin-12cell-mediated immunityfish pathogensinterleukin 12intracellular bacteria

Identifiers

PMID31501250
PMCPMC6803335
OpenAlexW2971375312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.