Evidence map›Paper›PMID 31501225›Full record

ArticleMolecular & cellular proteomics : MCP2019

N-glycopeptide Signatures of IgA

Shu Zhang, Xinyi Cao, Chao Liu, Wei Li, Wenfeng Zeng, Baiwen Li, Hao Chi, Mingqi Liu, Xue Qin, Lingyi Tang and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Role of Complement in Liver Diseases.Seminars in liver disease · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. 3D Structures of IgA, IgM, and Components.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 3 countries.

Shu ZhangLiver Cancer Institute, Zhongshan Hospital, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Fudan University, Shanghai 200032, China.
Xinyi CaoInstitutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Chao LiuBeijing Advanced Innovation Center for Precision Medicine, Beihang University, Beijing 100083, China.
Wei LiInstitutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Wenfeng ZengKey Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS), Institute of Computing Technology, CAS, Beijing 100190, China.
Baiwen LiDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai 201620, China.
Hao ChiKey Lab of Intelligent Information Processing of Chinese Academy of Sciences (CAS), Institute of Computing Technology, CAS, Beijing 100190, China.
Mingqi LiuInstitutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Xue QinDepartment of Clinical Laboratory, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi, China.
Lingyi TangSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Guoquan YanInstitutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Zefan GeState Key Laboratory for Novel Software Technology, Nanjing University, Nanjing 210046, China.
Yinkun LiuLiver Cancer Institute, Zhongshan Hospital, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Fudan University, Shanghai 200032, China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Qiang GaoLiver Cancer Institute, Zhongshan Hospital, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Fudan University, Shanghai 200032, China. Electronic address: gao.qiang@zs-hospital.sh.cn.
Haojie LuInstitutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; Department of Chemistry, Fudan University, Shanghai 200433, China; NHC Key Laboratory of Glycoconjugates Research, Fudan University, Shanghai 200032, China. Electronic address: luhaojie@fudan.edu.cn.
Fudan University · CNChinese Academy of Sciences · CNBeihang University · CNGuangxi Medical University · CNNanjing University · CNShanghai First People's Hospital · CNThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-glycosylation alteration has been reported in liver diseases. Characterizing N-glycopeptides that correspond to N-glycan structure with specific site information enables better understanding of the molecular pathogenesis of liver damage and cancer. Here, unbiased quantification of N-glycopeptides of a cluster of serum glycoproteins with 40-55 kDa molecular weight (40-kDa band) was investigated in hepatitis B virus (HBV)-related liver diseases. We used an N-glycopeptide method based on

Indexed as

Carcinoma, HepatocellularCase-Control StudiesGlycopeptidesGlycoproteinsGlycosylationHepatitis BHepatitis B virusHumansImmunoglobulin ALiver NeoplasmsPolysaccharidesProteomeGlycopeptidesGlycoproteinsImmunoglobulin APolysaccharidesProteome40-kDa BandBiomarker: DiagnosticGlycomicsGlycopeptideGlycoproteomicsHBV-Related Liver DiseasesIgA2Liver DiseaseMass Spectrometry

Identifiers

PMID31501225
PMCPMC6823847
OpenAlexW2972788367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.