Evidence map›Paper›PMID 31501157›Full record

ArticleBlood advances2019

Persistence of skewed X-chromosome inactivation in pre-B acute lymphoblastic leukemia of a female ATRX mutation carrier.

Christian P Bradley, Cai Chen, Karolyn A Oetjen, Cheng Yan, Reema Panjwani, Sara Hauffe, Katherine R Calvo, Constance Yuan, Prapti Arvind Patel, Nathan D Montgomery and 5 more

Abstract readCase Reports
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Christian P BradleyHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Cai ChenAdmera Health, LLC, South Plainfield, NJ.
Karolyn A OetjenHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Cheng YanGenetron Health Technologies Inc., Research Triangle Park, NC.ORCID 0000-0002-2601-3665
Reema PanjwaniHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Sara HauffeHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Katherine R CalvoDepartment of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD.
Constance YuanFlow Cytometry Unit, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Prapti Arvind PatelHematologic Malignancies/BMT Program, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX.
Nathan D MontgomeryDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.ORCID 0000-0003-1765-6623
Matthew C FosterLeukemia, Lymphoma and Myeloma Program, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC; and.ORCID 0000-0002-6652-3838
Minoo BattiwallaHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
A John BarrettHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Richard J GibbonsWeatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-7680-9311
Sawa ItoHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.ORCID 0000-0002-6076-0234

Funding

The Role of microRNA in Hematologic MalignanciesZIACL090025 · CLC · CLINICAL CENTER · PI CALVO, KATHERINE · 2010 to 2025
$0k
Medical Research Council MC_UU_00016/3
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene SilencingAdultChromosomes, Human, XFemaleGerm-Line MutationHeterozygoteHumansPrecursor B-Cell Lymphoblastic Leukemia-LymphomaX-linked Nuclear ProteinATRX protein, humanX-linked Nuclear Protein

Identifiers

PMID31501157
PMCPMC6737413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.