Evidence map›Paper›PMID 31501144›Full record

ArticleAntimicrobial agents and chemotherapy2019

Adaptation of Mycobacterium tuberculosis to Biofilm Growth Is Genetically Linked to Drug Tolerance.

Jacob P Richards, Wenlong Cai, Nicholas A Zill, Wenjun Zhang, Anil K Ojha

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Journal of bacteriology · 2026
    Article
  3. Molecular Mechanisms Underlying Antimicrobial Resistance in Mycobacteria.International journal of molecular sciences · 2026
    Review
  4. mSystems · 2026
    Article
  5. Article
  6. Review
  7. Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Review
  8. Article
  9. Article
  10. Loss ofbioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Expression ofFrontiers in cellular and infection microbiology · 2025
    Article
  13. Review
  14. Article
  15. ImmunoTargets and therapy · 2024
    Review
  16. Article
  17. Characterization ofAntimicrobial agents and chemotherapy · 2023
    Article
  18. Review
  19. Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. TheMicroorganisms · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacob P RichardsDivision of Genetics, Wadsworth Center, New York State Department of Health, Albany, New York, USA.
Wenlong CaiDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, California, USA.
Nicholas A ZillDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, California, USA.
Wenjun ZhangDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, California, USA.
Anil K OjhaDivision of Genetics, Wadsworth Center, New York State Department of Health, Albany, New York, USA anil.ojha@health.ny.gov.

Funding

Alternative Ribosomes & Antibiotic Tolerance in MycobacteriaR01AI132422 · NIAID · WADSWORTH CENTER · PI RAJENDRA K AGRAWAL, Anil Kumar Ojha · 2017 to 2026
$3.8M
In Situ Natural Product Labeling and ApplicationsDP2AT009148 · NCCIH · UNIVERSITY OF CALIFORNIA BERKELEY · PI ZHANG, WENJUN · 2015 to 2020
$2.8M
High Definition Ion Mobility SpectrometerS10OD020062 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI WILLIAMS, EVAN R · 2015 to 2015
$590k
Physiology of Mycobacterium Tuberculosis with Hibernating RibosomesR21AI144474 · NIAID · WADSWORTH CENTER · PI OJHA, ANIL KUMAR · 2019 to 2020
$466k
NCCIH NIH HHS DP2 AT009148NIAID NIH HHS R01 AI132422NIAID NIH HHS R21 AI144474NIH HHS S10 OD020062
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptation, PhysiologicalAntitubercular AgentsBiofilmsDrug Resistance, BacterialMycobacterium tuberculosisAntitubercular Agentsantibioticsbiofilmspersistencetuberculosis

Identifiers

PMID31501144
PMCPMC6811442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.