Evidence map›Paper›PMID 31501134›Full record

ArticleBMJ open2019

Mortality and potential years of life lost attributable to non-optimal glycaemic control in men and women with diabetes in the United Arab Emirates: a population-based retrospective cohort study.

Saif Al-Shamsi, Romona Devi Govender, Elpidoforos S Soteriades

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Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Saif Al-ShamsiInternal Medicine, United Arab Emirates University College of Medicine and Health Sciences, Al Ain, United Arab Emirates salshamsi@uaeu.ac.ae.ORCID 0000-0001-9755-3493
Romona Devi GovenderFamily Medicine, United Arab Emirates University College of Medicine and Health Sciences, Al Ain, United Arab Emirates.
Elpidoforos S SoteriadesInstitute of Public Health, United Arab Emirates University College of Medicine and Health Sciences, Al Ain, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesNumerous studies reported that achieving near-normal glycated haemoglobin (HbA1c) levels in patients with diabetes may delay or even prevent vascular complications. However, information regarding the impact of non-optimal HbA1c control on adverse health outcomes in an Arab population is unknown. The aim of this study was to estimate the fraction of deaths and potential years of life lost (PYLL) attributable to non-optimal HbA1c control among Emirati men and women with diabetes in the United Arab Emirates (UAE).

designA retrospective cohort study.

settingThis study was conducted in outpatient clinics at a tertiary care centre in Al Ain, UAE, between April 2008 and September 2018.

participantsThe sample comprised of 583 adult UAE nationals, aged≥18 years, with diabetes. Overall, 57% (n=332) of the study participants were men and 43% (n=251) were women. EXPOSURE: Non-optimal HbA1c control, defined as HbA1c≥6.5%. PRIMARY OUTCOME MEASURE: All-cause mortality, defined as death from any cause.

resultsAt the end of the 9-year follow-up period, 86 (14.8%) participants died. Overall, up to 33% (95% CI 2% to 63%) of deaths were attributable to non-optimal HbA1c control among patients with diabetes mellitus (DM). Stratified by sex, the adjusted fraction of avoidable mortality was 17% (95% CI -23% to 57%) for men and 50% (95% CI 3% to 98%) for women. Both deaths and PYLL attributable to non-optimal HbA1c control were higher in women compared with men.

conclusionsUp to one-third of all deaths in adult UAE nationals with DM could be attributed to non-optimal HbA1c control. Effective sex-specific interventions and healthcare quality-improvement programmes should urgently be implemented.

Indexed as

Diabetes MellitusLife ExpectancyAftercareCohort StudiesFemaleGlycated HemoglobinHumansMaleMiddle AgedMortalityRetrospective StudiesRisk FactorsTertiary Health CareUnited Arab EmiratesGlycated Hemoglobindiabetesglycated haemoglobinmortalitypopulation-attributable fractionpotential years of life lostUnited Arab Emirates

Identifiers

PMID31501134
PMCPMC6738721

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.