ArticleBMC plant biology2019
GhFAD2-3 is required for anther development in Gossypium hirsutum.
Article in BMC plant biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advancements in Crop PUFAs Biosynthesis and Genetic Engineering: A Systematic and Mixed Review System.International journal of molecular sciences · 2025Pooled it
- Evolutionary origin and asymmetric subgenomic retention of the lncRNAFrontiers in plant science · 2026Article
- Decreases in polyunsaturated fatty acid content improve heat stress tolerance during flowering and silicle development in pennycress (Frontiers in plant science · 2026Article
- Comparative Study of Fatty Acid Desaturase (FAD) Members Reveals Their Differential Roles in Upland Cotton.Plants (Basel, Switzerland) · 2025Article
- pseudo-GhFAD2-1 Is a lncRNA Involved in Regulating Cottonseed Oleic and Linoleic Acid Ratios and Seed Size in Gossypium hirsutum.Plant biotechnology journal · 2025Article
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- Genetic basis for broad interspecific compatibility in Solanum verrucosum.The Plant journal : for cell and molecular biology · 2025Article
- Bioengineering of Soybean Oil and Its Impact on Agronomic Traits.International journal of molecular sciences · 2023Review
- Insights into the NovelGenes · 2022Article
- Impact of water deficiency on leaf cuticle lipids and gene expression networks in cotton (Gossypium hirsutum L.).BMC plant biology · 2022Article
- Comparative Analysis and Structural Modeling ofBiology · 2022Article
- Explore the gene network regulating the composition of fatty acids in cottonseed.BMC plant biology · 2021Article
- GhPLP2 Positively Regulates Cotton Resistance to Verticillium Wilt by Modulating Fatty Acid Accumulation and Jasmonic Acid Signaling Pathway.Frontiers in plant science · 2021Article
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- Characterization and transcriptome analysis of a dominant genic male sterile cotton mutant.BMC plant biology · 2020Article
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Authors and funding
9 authors.
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Abstract
backgroundIn higher plants, the FAD2 gene encodes the microsomal oleate
resultsWe reported the molecular characterization of the cotton (Gossypium hirsutum) GhFAD2 gene family and the essential role of GhFAD2-3 in cotton anther development. G. hirsutum contains four pairs of homoeologous FAD2 genes (GhFAD2-1 to GhFAD2-4). GhFAD2-3 is ubiquitously and relatively highly expressed in all analyzed tissues, particularly in anthers. Specific inhibition of GhFAD2-3 using the RNA interference approach resulted in male sterility due to impaired anther development at the stages from meiosis to maturation. The cellular phenotypic abnormality observed at the meiosis stage of the GhFAD2-3 silenced plant (fad2-3) coincides with the significant reduction of C18:2 in anthers at the same stage. Compared with that of the wild type (WT), the content of C18:1 was 41.48%, which increased by 5 fold in the fad2-3 anther at the pollen maturation stage. Moreover, the ratio of monounsaturated to polyunsaturated fatty acid was 5.43 in fad2-3 anther, which was much higher than that of the WT (only 0.39). Through compositional analysis of anthers cuticle and transcriptome data, we demonstrated it was unfavorable to the development of anther by regulating GhFAD2-3 expression level to increase the oleic acid content.
conclusionsOur work demonstrated the importance of C18:2 and/or C18:3 in the development of the pollen exine and anther cuticle in cotton and provided clue for further investigation of the physiological significance of the fatty acid composition for plant growth and development.
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