Evidence map›Paper›PMID 31500506›Full record

ArticleCancer biology & therapy

Long noncoding RNA MALAT1 knockdown inhibits progression of anaplastic thyroid carcinoma by regulating miR-200a-3p/FOXA1.

Lisha Gou, Huawei Zou, Beibei Li

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Cancer biology & therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Lisha GouDepartment of Endocrine, Zhoukou Central Hospital , Zhoukou , Henam , 466000 , China.
Huawei ZouDepartment of Thyroid Surgery, Zhoukou Central Hospital , Zhoukou , Henan , China.
Beibei LiDepartment of Endocrine, Zhoukou Central Hospital , Zhoukou , Henam , 466000 , China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) have been reported to play essential roles in progression of thyroid carcinoma. However, the roles of lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in anaplastic thyroid carcinoma (ATC) process and its mechanism remain not been fully established. In this study, we focused on the effect of MALAT1 on cell proliferation, apoptosis, migration, invasion, and autophagy formation in ATC and explored the interaction between miR-200a-3p and MALAT1 or FOXA1. Moreover, murine xenograft model was established to investigate the roles and mechanism of MALAT1 in ATC progression

Indexed as

AnimalsApoptosisCarcinogenesisCell Line, TumorCell MovementCell ProliferationDisease ProgressionGene Expression Regulation, NeoplasticHepatocyte Nuclear Factor 3-alphaHeterograftsHumansMiceMicroRNAsNeoplasm InvasivenessRNA, Long NoncodingThyroid Carcinoma, AnaplasticFOXA1 protein, humanHepatocyte Nuclear Factor 3-alphaMALAT1 long non-coding RNA, humanMicroRNAsMIRN200 microRNA, humanRNA, Long NoncodingAnaplastic thyroid carcinomaFOXA1MALAT1miR-200a-3p

Identifiers

PMID31500506
PMCPMC6804806
OpenAlexW2972916078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.