Evidence map›Paper›PMID 31500403›Full record

ArticleUltrasonography (Seoul, Korea)2019

Inter-platform reproducibility of liver stiffness measured with two different point shear wave elastography techniques and 2-dimensional shear wave elastography using the comb-push technique.

Hwaseong Ryu, Su Joa Ahn, Jeong Hee Yoon, Jeong Min Lee

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Article in Ultrasonography (Seoul, Korea), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

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10citing papers in PubMed
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1 · What the graph read from it

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10 citing papers in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Hwaseong RyuDepartment of Radiology, Pusan National University Yangsan Hospital, Yangsan, Korea.
Su Joa AhnDepartment of Radiology, Gachon University Gil Medical Center, Incheon, Korea.
Jeong Hee YoonDepartment of Radiology, Seoul National University Hospital, Seoul, Korea.
Jeong Min LeeDepartment of Radiology, Seoul National University Hospital, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to compare the technical success rate and reliability of measurements made using three shear wave elastography (SWE) techniques and to assess the inter-platform reproducibility of the resultant liver stiffness measurements.

methodsThis prospective study included 54 patients with liver disease. Liver stiffness (LS) measurements were obtained using 2-point SWE techniques (Virtual Touch Quantification and S-Shearwave) and 2-dimensional (2D) SWE, with transient elastography (TE) serving as the reference standard. The technical success rates and measurement reliability of the three techniques were compared. LS values measured using the three SWE techniques and TE were compared using Spearman correlation coefficients and 95% Bland-Altman limits of agreement. Intra-class correlation coefficients (ICC) were used to analyze the inter-platform reproducibility of LS measurements.

resultsThe three SWE techniques and TE showed similar technical success rates (P=0.682) but demonstrated significant differences in the reliability of LS measurements (P=0.006) and mean LS measurements (P<0.001). Despite strong correlations (r=0.73-0.94) between SWE systems, various degrees of inter-platform reproducibility (ICC, 0.58-0.92) were observed for the three SWE techniques. The best agreement was observed between S-Shearwave and TE (ICC, 0.92), and the worst agreement was observed between 2D-SWE and TE (ICC, 0.58). In the BlandAltman analysis, a tendency toward lower LS values with the three SWE techniques than with TE in patients with F3 and F4 disease was observed.

conclusionSignificant inter-system variability was observed in LS measurements made using the three SWE techniques. Therefore, LS values measured using different SWE techniques should not be used interchangeably for longitudinal follow-up.

Indexed as

Liver fibrosisLiver stiffnessShear wave elastographyUltrasound elastography

Identifiers

PMID31500403
PMCPMC6769187

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