ArticleAntioxidants (Basel, Switzerland)2019
Recovery of Polyphenols from Brewer's Spent Grains.
Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The trial behind it
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Who cites it
35 citing papers in PubMed, 84 citations in OpenAlex.
- Trial
- Towards Sustainable Recovery of Phenolics, Proteins, and Arabinoxylans from Brewer's Spent Grain Through Deep Eutectic Solvents: Extraction Strategies, Structure-Function Relationships, and Food Biorefinery Perspective.Foods (Basel, Switzerland) · 2026Review
- Valorization of Brewing By-Products for Sustainable Active Material.Foods (Basel, Switzerland) · 2026Article
- Brewer's Spent Grain Flour: Chemical Composition, Functional Properties, and Influence on Gut Microbiota.Foods (Basel, Switzerland) · 2026Article
- Techno-Economic Feasibility of Functional Snacks from Brewer's Spent Grain and Sweet Potato: A Simulation Study.Foods (Basel, Switzerland) · 2026Article
- Mechanism-Driven Green Extraction of Plant Polyphenols: From Molecular Interactions to Process Integration and Intelligent Optimization.Plants (Basel, Switzerland) · 2026Review
- Functional Benefits of Brewer's Spent Grain and the Challenge of Developing Food Ingredients for Human Health.Antioxidants (Basel, Switzerland) · 2026Review
- Sensory Evaluation of Vanillin Obtained by Fungi in the Solid-State Fermentation from Agri-Food Industry By-Products.Molecules (Basel, Switzerland) · 2025Article
- Nutritional Value of Brewer's Spent Grain and Consumer Acceptance of Its Value-Added Food Products.Foods (Basel, Switzerland) · 2025Review
- Impact of Wet Brewer's Grain Supplementation in Bovine Dietary on Fatty Acids Profile, Vitamin E and Sensory Properties of Fresh Cheese.Food science of animal resources · 2025Article
- Article
- Brewer's spent grain: Unveiling innovative applications in the food and packaging industry.Comprehensive reviews in food science and food safety · 2025Review
- Applying Subcritical Water Extraction to Obtain Bioactive Compounds and Cellulose Fibers from Brewer Spent Grains.Molecules (Basel, Switzerland) · 2024Article
- High-Temperature Hydrothermal Extraction of Phenolic Compounds from Brewer's Spent Grain and Malt Dust Biomass Using Natural Deep Eutectic Solvents.Molecules (Basel, Switzerland) · 2024Article
- Study of Brewer's Spent Grain Environmentally Friendly Processing Ways.Molecules (Basel, Switzerland) · 2023Article
- Characterization of brewer's spent grain extracts by tandem mass spectrometry and HPLC-DAD: Ferulic acid dehydrodimers, phenolamides, and oxylipins.Food science & nutrition · 2023Article
- Functional Bread Produced in a Circular Economy Perspective: The Use of Brewers' Spent Grain.Foods (Basel, Switzerland) · 2023Article
- Improvement of the Nutraceutical Profile of Brewer's Spent Grain after Treatment withMicroorganisms · 2022Article
- Analysis of Phenolic Compounds in Food by Coulometric Array Detector: A Review.Sensors (Basel, Switzerland) · 2022Review
- Cereal Waste Valorization through Conventional and Current Extraction Techniques-An Up-to-Date Overview.Foods (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
The recovery of antioxidant polyphenols from light, dark and mix brewer's spent grain (BSG) using conventional maceration, microwave and ultrasound assisted extraction was investigated. Total polyphenols were measured in the crude (60% acetone), liquor extracts (saponified with 0.75% NaOH) and in their acidified ethyl acetate (EtOAc) partitioned fractions both by spectrophotometry involving Folin-Ciocalteu reagent and liquid-chromatography-tandem mass spectrometry (LC-MS/MS) methods. Irrespective of the extraction methods used, saponification of BSG yielded higher polyphenols than in the crude extracts. The EtOAc fractionations yielded the highest total phenolic content (TPC) ranging from 3.01 ± 0.19 to 4.71 ± 0.28 mg gallic acid equivalent per g of BSG dry weight. The corresponding total polyphenols quantified by LC-MS/MS ranged from 549.9 ± 41.5 to 2741.1 ± 5.2 µg/g of BSG dry weight. Microwave and ultrasound with the parameters and equipment used did not improve the total polyphenol yield when compared to the conventional maceration method. Furthermore, the spectrophotometric quantification of the liquors overestimated the TPC, while the LC-MS/MS quantification gave a closer representation of the total polyphenols in all the extracts. The total polyphenols were in the following order in the EtOAc fractions: BSG light > BSG Mix > BSG dark, and thus suggested BSG light as a sustainable, low cost source of natural antioxidants that may be tapped for applications in food and phytopharmaceutical industries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.