Evidence map›Paper›PMID 31500197›Full record

ArticleCancers2019

A Tunable Nanoplatform of Nanogold Functionalised with Angiogenin Peptides for Anti-Angiogenic Therapy of Brain Tumours.

Irina Naletova, Lorena Maria Cucci, Floriana D'Angeli, Carmelina Daniela Anfuso, Antonio Magrì, Diego La Mendola, Gabriella Lupo, Cristina Satriano

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Peptides Derived from Angiogenin Regulate Cellular Copper Uptake.International journal of molecular sciences · 2021
    Article
  11. Article
  12. An ATFCancer biology & medicine · 2020
    Article
  13. Cancer Nanomedicine.Cancers · 2020
    Article
  14. Hyaluronan-Metal Gold Nanoparticle Hybrids for Targeted Tumor Cell Therapy.International journal of molecular sciences · 2020
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Irina NaletovaConsorzio Interuniversitario di Ricerca in Chimica dei Metalli nei Sistemi Biologici (CIRCMSB), Via Celso Ulpiani 27, I-70126 Bari, Italy. irina_naletova@yahoo.com.
Lorena Maria CucciHybrid NanobioInterfaces Lab (NHIL), Department of Chemical Sciences, University of Catania, Viale Andrea Doria 6, I-95125 Catania, Italy. lorena.cucci@unict.it.
Floriana D'AngeliDepartment of Biomedical and Biotechnological Sciences, University of Catania, Via Santa Sofia 89, I-95123 Catania, Italy. fdangeli@unict.it.
Carmelina Daniela AnfusoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Via Santa Sofia 89, I-95123 Catania, Italy. daniela.anfuso@unict.it.
Antonio MagrìInstitute of Crystallography Catania, National Council of Research (IC-CNR), Via Paolo Gaifami 18, I-95126 Catania, Italy. leotony@unict.it.
Diego La MendolaConsorzio Interuniversitario di Ricerca in Chimica dei Metalli nei Sistemi Biologici (CIRCMSB), Via Celso Ulpiani 27, I-70126 Bari, Italy. lamendola@farm.unipi.it.
Gabriella LupoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Via Santa Sofia 89, I-95123 Catania, Italy. gabriella.lupo@unict.it.
Cristina SatrianoConsorzio Interuniversitario di Ricerca in Chimica dei Metalli nei Sistemi Biologici (CIRCMSB), Via Celso Ulpiani 27, I-70126 Bari, Italy. csatriano@unict.it.
University of Catania · ITConsorzio Interuniversitario Reattività Chimica e Catalisi · ITInstitute of Crystallography · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenin (ANG), an endogenous protein that plays a key role in cell growth and survival, has been scrutinised here as promising nanomedicine tool for the modulation of pro-/anti-angiogenic processes in brain cancer therapy. Specifically, peptide fragments from the putative cell membrane binding domain (residues 60-68) of the protein were used in this study to obtain peptide-functionalised spherical gold nanoparticles (AuNPs) of about 10 nm and 30 nm in optical and hydrodynamic size, respectively. Different hybrid biointerfaces were fabricated by peptide physical adsorption (Ang

Indexed as

actincopperdifferentiated neuroblastomaglioblastomananomedicinepeptidomimeticsplasmonicsreal-time quantitative polymerase chain reaction (qPCR)theranosticsVEGF

Identifiers

PMID31500197
PMCPMC6770958
OpenAlexW2971743225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.