Evidence map›Paper›PMID 31500157›Full record

ArticlePharmaceutics2019

Metal-Organic Framework-Based Chemo-Photothermal Combinational System for Precise, Rapid, and Efficient Antibacterial Therapeutics.

Biyuan Wu, Jintao Fu, Yixian Zhou, Jing Wang, Xiaoqian Feng, Yiting Zhao, Guiling Zhou, Chao Lu, Guilan Quan, Xin Pan and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Biyuan WuSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. wuby7@mail2.sysu.edu.cn.
Jintao FuSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. fujt7@mail2.sysu.edu.cn.
Yixian ZhouSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhouyx36@mail2.sysu.edu.cn.
Jing WangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. wangj527@mail2.sysu.edu.cn.
Xiaoqian FengSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. fengxq23@mail2.sysu.edu.cn.
Yiting ZhaoSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhaoyt8@mail2.sysu.edu.cn.
Guiling ZhouSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhougling@mail2.sysu.edu.cn.
Chao LuSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. luch9@mail.sysu.edu.cn.
Guilan QuanSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. quanglan@mail.sysu.edu.cn.
Xin PanSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. panxin2@mail.sysu.edu.cn.
Chuanbin WuSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. wuchuanb@mail.sysu.edu.cn.
Sun Yat-sen University · CN

Funding

111 project B16047China Postdoctoral Science Foundation 2018M633259National Nature Science Foundation of China 81803466National Nature Science Foundation of China 81803467
6 · The paper itself

Abstract

Rapid increase of antimicrobial resistance has become an urgent threat to global public health. In this research, since photothermal therapy is a potential antibacterial strategy, which is less likely to cause resistance, a metal-organic framework-based chemo-photothermal combinational system was constructed. Zeolitic imidazolate frameworks-8 (ZIF-8), a porous carrier with unique features such as high loading and pH-sensitive degradation, was synthesized, and then encapsulated photothermal agent indocyanine green (ICG). First, ICG with improved stability in ZIF-8 (ZIF-8-ICG) can effectively produce heat in response to NIR laser irradiation for precise, rapid, and efficient photothermal bacterial ablation. Meanwhile, Zn

Indexed as

anti-bacteriachemo-photothermal combination therapyindocyanine greenmetal–organic frameworks

Identifiers

PMID31500157
PMCPMC6781304
OpenAlexW2971959214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.