Evidence map›Paper›PMID 31500117›Full record

ArticleInternational journal of molecular sciences2019

Effect of Tff3 Deficiency and ER Stress in the Liver.

Kate Šešelja, Iva Bazina, Jessica Welss, Martin Schicht, Friedrich Paulsen, Nikola Bijelić, Edi Rođak, Anita Horvatić, Andrea Gelemanović, Martina Mihalj and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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  9. Trefoil Factor Protein 3 (TFF3) as a Guardian of the Urinary Bladder Epithelium.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Kate ŠešeljaDepartment of Molecular Medicine, Ruđer Bošković Institute, Bijenička 54, 10 000 Zagreb, Croatia.
Iva BazinaDepartment of Molecular Medicine, Ruđer Bošković Institute, Bijenička 54, 10 000 Zagreb, Croatia.
Jessica WelssInstitute of Functional and Clinical Anatomy, Faculty of Medicine, Friedrich-Alexander-University Erlangen-Nürnberg, 91051 Erlangen, Germany.
Martin SchichtInstitute of Functional and Clinical Anatomy, Faculty of Medicine, Friedrich-Alexander-University Erlangen-Nürnberg, 91051 Erlangen, Germany.
Friedrich PaulsenInstitute of Functional and Clinical Anatomy, Faculty of Medicine, Friedrich-Alexander-University Erlangen-Nürnberg, 91051 Erlangen, Germany.
Nikola BijelićDepartment of Histology and Embryology, Faculty of Medicine, University of Osijek, J. Huttlera 4, HR-31000 Osijek, Croatia.
Edi RođakDepartment of Histology and Embryology, Faculty of Medicine, University of Osijek, J. Huttlera 4, HR-31000 Osijek, Croatia.ORCID 0000-0001-7814-2031
Anita HorvatićERA Chaire Team, Proteomics Laboratory, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10 000 Zagreb, Croatia.
Andrea GelemanovićERA Chaire Team, Proteomics Laboratory, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10 000 Zagreb, Croatia.
Martina MihaljDepartment of Physiology and Immunology, Faculty of Medicine, University of Osijek, J. Huttlera 4, HR-31000 Osijek, Croatia.
Mirela Baus LončarDepartment of Molecular Medicine, Ruđer Bošković Institute, Bijenička 54, 10 000 Zagreb, Croatia. mbaus@irb.hr.ORCID 0000-0002-6940-2302
Friedrich-Alexander-Universität Erlangen-Nürnberg · DERuđer Bošković Institute · HRUniversity of Osijek · HRUniversity of Zagreb · HR

Funding

Croatian Science Foundation grant IP-06-2016-2717European Structural Fond 2014-2020 financial support for PhD student I. Bazina
6 · The paper itself

Abstract

Endoplasmic reticulum (ER) stress, a cellular condition caused by the accumulation of unfolded proteins inside the ER, has been recognized as a major pathological mechanism in a variety of conditions, including cancer, metabolic and neurodegenerative diseases. Trefoil factor family (TFFs) peptides are present in different epithelial organs, blood supply, neural tissues, as well as in the liver, and their deficiency has been linked to the ER function. Complete ablation of

Indexed as

AnimalsBiomarkersCytokinesDisease Models, AnimalEndoplasmic Reticulum StressGene ExpressionLiverMiceMice, KnockoutOxidative StressProteomeProteomicsTrefoil Factor-3BiomarkersCytokinesProteomeTff3 protein, mouseTrefoil Factor-3ER stressliverproinflammatory cytokinestrefoil peptide 3tunicamycin

Identifiers

PMID31500117
PMCPMC6770867
OpenAlexW2972129215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.