Evidence map›Paper›PMID 31499517›Full record

ArticlePloS one2019

Comparison of risk models for mortality and cardiovascular events between machine learning and conventional logistic regression analysis.

Shinya Suzuki, Takeshi Yamashita, Tsuyoshi Sakama, Takuto Arita, Naoharu Yagi, Takayuki Otsuka, Hiroaki Semba, Hiroto Kano, Shunsuke Matsuno, Yuko Kato and 4 more

Erratum issuedAbstract readComparative Study
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Shinya SuzukiDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.ORCID 0000-0002-4769-5925
Takeshi YamashitaDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Tsuyoshi SakamaSigmaxyz, Inc, Tokyo, Japan.
Takuto AritaDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Naoharu YagiDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Takayuki OtsukaDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Hiroaki SembaDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Hiroto KanoDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Shunsuke MatsunoDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Yuko KatoDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Tokuhisa UejimaDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Yuji OikawaDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Minoru MatsuhamaDepartment of Cardiovascular Surgery, The Cardiovascular Institute, Tokyo, Japan.
Junji YajimaDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsNon-linear models by machine learning may identify different risk factors with different weighting in comparison to conventional linear models. METHODS AND

resultsThe analyses were performed in 15,933 patients included in the Shinken Database (SD) 2004-2014 (n = 22,022) for whom baseline data of blood sampling and ultrasound cardiogram and follow-up data at 2 years were available. Using non-linear models with machine learning software, 118 risk factors and their weighting of risk for all-cause mortality, heart failure (HF), acute coronary syndrome (ACS), ischemic stroke (IS), and intracranial hemorrhage (ICH) were identified, where the top two risk factors were albumin/hemoglobin, left ventricular ejection fraction/history of HF, history of ACS/anti-platelet use, history of IS/deceleration time, and history of ICH/warfarin use. The areas under the curve of the developed models for each event were 0.900, 0.912, 0.879, 0.758, and 0.753, respectively.

conclusionHere, we described our experience with the development of models for predicting cardiovascular prognosis by machine learning. Machine learning could identify risk predicting models with good predictive capability and good discrimination of the risk impact.

Indexed as

Machine LearningModels, StatisticalCardiovascular DiseasesCohort StudiesFemaleHumansLogistic ModelsMaleMiddle AgedRisk Assessment

Identifiers

PMID31499517
PMCPMC6733605

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.