Evidence map›Paper›PMID 31499012›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Galectin-1 interacts with the human endogenous retroviral envelope protein syncytin-2 and potentiates trophoblast fusion in humans.

Caroline Toudic, Amandine Vargas, Yong Xiao, Guillaume St-Pierre, Norbert Bannert, Julie Lafond, Éric Rassart, Sachiko Sato, Benoit Barbeau

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Gal-2 Increases H3K4meBiomolecules · 2022
    Article
  7. Article
  8. Misrepresentation about vaccines that are scaring women.African journal of primary health care & family medicine · 2021
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Caroline ToudicDépartement des Sciences Biologiques, Centre de Recherche BioMed, Université du Quebec à Montréal, Montreal, Quebec, Canada.
Amandine VargasDépartement des Sciences Biologiques, Centre de Recherche BioMed, Université du Quebec à Montréal, Montreal, Quebec, Canada.
Yong XiaoDépartement des Sciences Biologiques, Centre de Recherche BioMed, Université du Quebec à Montréal, Montreal, Quebec, Canada.
Guillaume St-PierreGlycobiology and Bioimaging Laboratory, Research Centre for Infectious Diseases, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada.
Norbert BannertRobert-Koch Institute, Berlin, Germany.
Julie LafondDépartement des Sciences Biologiques, Centre de Recherche BioMed, Université du Quebec à Montréal, Montreal, Quebec, Canada.
Éric RassartDépartement des Sciences Biologiques, Centre de Recherche BioMed, Université du Quebec à Montréal, Montreal, Quebec, Canada.
Sachiko SatoGlycobiology and Bioimaging Laboratory, Research Centre for Infectious Diseases, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada.
Benoit BarbeauDépartement des Sciences Biologiques, Centre de Recherche BioMed, Université du Quebec à Montréal, Montreal, Quebec, Canada.
Université du Québec à Montréal · CAUniversité Laval · CARobert Koch Institute · DE

Funding

CIHR MOP130561
6 · The paper itself

Abstract

Syncytin (Syn)-2 is an important fusogenic protein that contributes to the formation of the placental syncytiotrophoblast. Galectin (Gal)-1, a soluble lectin, is also involved in trophoblast cell fusion and modulates the interaction of certain retroviral envelopes with their cellular receptor. This study aimed to investigate the association between Syn-2 and Gal-1 during human trophoblast cell fusion. This association was evaluated

Indexed as

Cell FusionEndogenous RetrovirusesFemaleGalectin 1HEK293 CellsHeLa CellsHumansPregnancyPregnancy ProteinsProtein BindingTrophoblastsERVFRD-1 protein, humanGalectin 1Pregnancy ProteinsERVFRD-1syncytializationvillous cytotrophoblastsβ-galactoside-binding lectin

Identifiers

PMID31499012
PMCPMC6902695
OpenAlexW2973041165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.