ArticleeLife2019
Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca
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In one paragraph
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
51 citing papers in PubMed, 90 citations in OpenAlex.
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- Immunoglobulin binding protein (BiP) forms two types of dimers.Protein science : a publication of the Protein Society · 2026Article
- Crosstalk collapse: mitochondria-centric organelle network disruption in ovarian aging.Cell communication and signaling : CCS · 2026Review
- Inhibition of FicD-mediated AMPylation and deAMPylation by isoprenoid diphosphates.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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- Calcium signaling hypothesis: A non-negligible pathogenesis in Alzheimer's disease.Journal of advanced research · 2025Review
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- Biomolecular Basis of Life.Metabolites · 2025Review
- SERCA-mediated endoplasmic reticulum stress facilitates hematopoietic stem cell mobilization.Stem cell research & therapy · 2025Article
- Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis.Molecular cell · 2025Review
- Selective activation of antioxidant resources and energy deficiency in Marinesco-Sjögren syndrome fibroblasts as an adaptive biological response to Sil1 loss.Scientific reports · 2025Article
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- Serine-129 phosphorylatedFrontiers in aging neuroscience · 2025Article
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- Exploring proinsulin proteostasis: insights into beta cell health and diabetes.Frontiers in molecular biosciences · 2025Review
- Mitochondria-Targeted Biomaterials-Regulating Macrophage Polarization Opens New Perspectives for Disease Treatment.International journal of nanomedicine · 2025Review
- Targeting translocator protein protects against myocardial ischemia/reperfusion injury by alleviating mitochondrial dysfunction.Experimental and therapeutic medicine · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Jing YongDegenerative Diseases Program, SBP Medical Discovery Institute, La Jolla, United States.ORCID 0000-0002-4970-408X
Helmut BischofMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.ORCID 0000-0003-2380-600X
Sandra BurgstallerMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Marina SiirinDegenerative Diseases Program, SBP Medical Discovery Institute, La Jolla, United States.
Anne MurphyDepartment of Pharmacology, University of California, San Diego, La Jolla, United States.
Roland MalliMolecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.ORCID 0000-0001-6327-8729
Randal J KaufmanDegenerative Diseases Program, SBP Medical Discovery Institute, La Jolla, United States.ORCID 0000-0003-4277-316X
Discovery Institute · USMedical University of Graz · ATUniversity of California San Diego · US
Funding
Tumor Microenvironment and Cancer ImmunologyP30CA030199 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI ELENA B PASQUALE · 1985 to 2026
$107.2MTransgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrea L Hevener · 2003 to 2026
$40.4MRegulation of Factor VIII SecretionR01HL052173 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KAUFMAN, RANDAL J. · 1995 to 2014
$6.5MRole of the Unfolded Protein Response in Beta CellR37DK042394 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KAUFMAN, RANDAL J. · 2007 to 2016
$4.9M"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"R01AG062190 · NIA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI HUANG, TIMOTHY YIKAI, KAUFMAN, RANDAL J. · 2019 to 2023
$4.8MModifiers of Proinsulin Influence T2D SusceptibilityR24DK110973 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI ARVAN, PETER, ITKIN-ANSARI, PAMELA ROSE · 2016 to 2019
$4.1MER stress and UPR in non-alcoholic steatohepatitis and hepatocellular carcinomaR01CA198103 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI KAUFMAN, RANDAL J. · 2016 to 2020
$3.4MHomeostatic Role of IRE1a-XBP1-PDI1 in Hepatic Lipid MetabolismR01DK103185 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI KAUFMAN, RANDAL J. · 2015 to 2019
$2.9MMechanism of ER Protein Misfolding-Induced Mitochondrial DysfunctionR01DK113171 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI KAUFMAN, RANDAL J. · 2017 to 2020
$2.5MAustrian Science Fund P28529-B27Austrian Science Fund FWF P 28529NCI NIH HHS P30 CA030199NCI NIH HHS P30CA030199NCI NIH HHS R01 CA198103NCI NIH HHS R01CA198103NHLBI NIH HHS R01 HL052173NHLBI NIH HHS R01HL052173NIA NIH HHS R01 AG062190NIA NIH HHS R01AG062190NIDDK NIH HHS P30 DK063491NIDDK NIH HHS P30DK063491NIDDK NIH HHS R01 DK103185NIDDK NIH HHS R01DK103185NIDDK NIH HHS R01 DK113171NIDDK NIH HHS R01DK113171NIDDK NIH HHS R24 DK110973NIDDK NIH HHS R24DK110973NIDDK NIH HHS R37 DK042394NIDDK NIH HHS R37DK042394
Abstract
The endoplasmic reticulum (
Indexed as
Adenosine TriphosphateAnimalsBiological TransportCalciumCations, DivalentCell LineCricetulusEndoplasmic ReticulumHumansMitochondriaRatsAdenosine TriphosphateCalciumCations, DivalentATP and adenosine nucleotides transportbiochemistrycell biologychemical biologyChinese hamster ovary cellER stressorganelle bioenergeticsprotein foldingSLC35B1/AXER protein
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.