Evidence map›Paper›PMID 31497886›Full record

ArticleClinical cardiology2019

ECG changes after percutaneous edge-to-edge mitral valve repair.

Hou Bo, David Heinzmann, Christian Grasshoff, Peter Rosenberger, Christian Schlensak, Meinrad Gawaz, Jürgen Schreieck, Harald F Langer, Johannes Patzelt, Peter Seizer

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Impact of pulmonary hypertension on outcomes after TEER in patients suffering from mitral regurgitation.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Hou BoDepartment of Cardiology and Angiology, University Hospital, Eberhard Karls University Tübingen, Tübingen, Germany.
David HeinzmannDepartment of Cardiology and Angiology, University Hospital, Eberhard Karls University Tübingen, Tübingen, Germany.ORCID https://orcid.org/0000-0003-1419-6801
Christian GrasshoffDepartment of Anaesthesiology, University Hospital, Eberhard Karls University Tübingen, Tübingen, Germany.
Peter RosenbergerDepartment of Anaesthesiology, University Hospital, Eberhard Karls University Tübingen, Tübingen, Germany.
Christian SchlensakDepartment of Cardiovascular Surgery, University Hospital, Eberhard Karls University Tübingen, Tübingen, Germany.
Meinrad GawazDepartment of Cardiology and Angiology, University Hospital, Eberhard Karls University Tübingen, Tübingen, Germany.
Jürgen SchreieckDepartment of Cardiology and Angiology, University Hospital, Eberhard Karls University Tübingen, Tübingen, Germany.
Harald F LangerMedical Clinic II, Universitäres Herzzentrum Lübeck, University Hospital Schleswig-Holstein, Germany.
Johannes PatzeltMedical Clinic II, Universitäres Herzzentrum Lübeck, University Hospital Schleswig-Holstein, Germany.
Peter SeizerDepartment of Cardiology and Angiology, University Hospital, Eberhard Karls University Tübingen, Tübingen, Germany.
University of Tübingen · DEUniversitäres Kinderwunschzentrum Lübeck · DEQingdao University · CN

Funding

Deutsche Forschungsgemeinschaft KFO 274Deutsche Forschungsgemeinschaft TRR 240Deutsche HerzstiftungMinistry of Science, Research and Arts, Baden-WürttembergVolkswagen Foundation
6 · The paper itself

Abstract

backgroundMitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effective procedure to reduce MR in high-risk patients, which are likely to suffer from atrial rhythm disturbances. So far, electroanatomical changes after PMVR have not been studied. HYPOTHESIS: In the current study, we investigated changes in surface electrocardiograms (ECGs) of patients undergoing PMVR for reduction of MR.

methodsWe evaluated 104 surface ECGs from patients in sinus rhythm undergoing PMVR. P wave duration, P wave amplitude, PR interval, QRS duration, QRS axis, and QT interval were evaluated before and after PMVR and at follow-up.

resultsWe found no changes in QRS duration, QRS axis, and QT interval after successful PMVR. However, P wave duration, amplitude, and PR interval were significantly decreased after reduction of MR through PMVR (P < .05, respectively).

conclusionThe data we provide offers insight into changes in atrial conduction after reduction of MR using PMVR in patients with sinus rhythm.

Indexed as

ElectrocardiographyAgedAtrial RemodelingCardiac Surgical ProceduresEchocardiographyEchocardiography, TransesophagealFemaleFollow-Up StudiesHeart AtriaHeart Conduction SystemHemodynamicsHumansMaleMitral ValveMitral Valve InsufficiencyPostoperative Periodatrial conductionatrial strainelectrocardiogrammitral regurgitationpercutaneous mitral valve repairremodeling

Identifiers

PMID31497886
PMCPMC6837028
OpenAlexW2972844606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.