ArticleHeliyon2019
The effect of anxiety on cognition in older adult inpatients with depression: results from a multicenter observational study.
Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Mental health in the peri-hospital period of older patients: the roles of physical symptoms burden and sleep quality.Age and ageing · 2026Article
- Depressive symptoms and cognitive impairment among rural Chinese older women: anxiety and poor sleep as sequential correlates-A cross-sectional analysis.Frontiers in public health · 2026Article
- The interrelationships among insomnia, frailty, anxiety, and cognitive function in middle-aged and older adults: a cross-sectional study.Frontiers in psychiatry · 2026Article
- Anxiety in late-life depression is associated with poorer performance across multiple cognitive domains.Journal of the International Neuropsychological Society : JINS · 2024Article
- Intersectional Inequalities in the Transition to Grandparenthood and Cognitive Functioning: A Longitudinal Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- The effect of anxiety and depression on cognition in older adults with severe-to-profound hearing loss.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Dimensions of cognitive reserve and their predictive power of cognitive performance and decline in the elderly.Frontiers in dementia · 2023Article
- Measuring depression in Primary Health Care in Spain: Psychometric properties and diagnostic accuracy of HSCL-5 and HSCL-10.Frontiers in medicine · 2022Article
- Heterogenous Subtypes of Late-Life Depression and Their Cognitive Patterns: A Latent Class Analysis.Frontiers in psychiatry · 2022Article
- Validation and Psychometric Properties of the Spanish Version of the Hopkins Symptom Checklist-25 Scale for Depression Detection in Primary Care.International journal of environmental research and public health · 2021Article
- [Translation and cross-cultural adaptation into Spanish, Catalan and Galician of the Hopkins Symptom Checklist-25 to identify depression in Primary Care].Atencion primaria · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Late-life depression is associated with reduced cognitive function beyond normal age-related cognitive deficits. As comorbid anxiety frequently occur in late-life depression, this study aimed to examine the association between anxiety symptoms and cognitive function among older inpatients treated for depression. We hypothesized that there would be an overall additive effect of comorbid anxiety symptoms on dysfunction across cognitive domains. The study included 142 patients treated for late-life depression in hospital, enrolled in the Prognosis of Depression in the Elderly study. Anxiety symptoms were measured at admission using the anxiety subscale of the Hospital Anxiety and Depression Scale. Patients completed cognitive tasks at admission and discharge. Linear mixed and generalized linear mixed models were estimated to investigate the effect of anxiety, on continuous and categorical cognitive scores, respectively, while controlling for depression. Anxiety severity at admission was not associated with performance in any of the cognitive domains. Patients with more symptoms of anxiety at admission demonstrated a significant improvement in immediate recall during the hospital stay. Patients with a score above cutoff indicating clinically significant symptoms on the anxiety subscale performed better on general cognitive function, as measured by the Mini Mental Status Examination at admission, than those below cutoff for anxiety. In conclusion, comorbid anxiety symptoms had no additive effect on cognitive dysfunction in late-life depression in our sample of inpatients.
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