ReviewFrontiers in pediatrics2019
Neonatal Cardiac ECMO in 2019 and Beyond.
Review in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Short-Term Mortality Among Pediatric Patients With Heart Diseases Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2023Pooled it
- Extracorporeal Membrane Oxygenation Outside the Operating Room in Neonates and Infants.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Extracorporeal Membrane Oxygenation in Anomalous Left Coronary Artery from the Pulmonary Artery.Pediatric cardiology · 2026Article
- Coronary artery anomalies in children: subtype classification, age of onset, clinical outcomes, and prognostic implications.BMC pediatrics · 2026Article
- Perioperative mortality and 1-year neurodevelopmental outcome after cardiac surgery prior to 6 weeks of age, requiring perioperative extracorporeal membrane oxygenation in the first year of life.Frontiers in cardiovascular medicine · 2026Article
- Evaluating the Prevalence of Optimal Neurodevelopmental Outcome at 2 Years in Children Previously on Ventricular Assist Device Support.Journal of the American Heart Association · 2025Article
- Perioperative extracorporeal membrane oxygenation in neonates with transposition of the great arteries: 15 years of experience.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025Article
- Electrical alternans of the Q-T interval and fatal arrhythmias caused by neonatal cardiac tumor: a case report.Frontiers in cardiovascular medicine · 2025Article
- Venoarterial extracorporeal membrane oxygenation using magnetic levitation centrifugal pumps for fulminant myocarditis in infants, children and young adults.Translational pediatrics · 2024Article
- Risk factors, incidence, and outcomes of neonatal respiratory extracorporeal membrane oxygenation including association with therapeutic hypothermia in California during 2013-2020.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- V-A ECMO for neonatal coxsackievirus B fulminant myocarditis: a case report and literature review.Frontiers in cardiovascular medicine · 2024Article
- Emergent bedside management of a pneumatocele in a neonate via Fogarty catheter.Clinical case reports · 2023Article
- Extracorporeal Membrane Oxygenation (ECMO): A Lifeline for Pregnant and Postpartum Women.Cureus · 2023Review
- Risk Factors and Outcomes of Children with Congenital Heart Disease on Extracorporeal Membrane Oxygenation-A Ten-Year Single-Center Report.Life (Basel, Switzerland) · 2023Article
- Extracorporeal Membrane Oxygenation Then and Now; Broadening Indications and Availability.Critical care clinics · 2023Review
- Severe neonatal enterovirus infection in twins with different outcomes: A case report.Frontiers in pediatrics · 2023Article
- Veno-Arterial Extracorporeal Membrane Oxygenation (ECMO) Impairs Bradykinin-Induced Relaxation in Neonatal Porcine Coronary Arteries.Biomedicines · 2022Article
- Extracorporeal Membrane Oxygenation in Congenital Heart Disease.Children (Basel, Switzerland) · 2022Review
- Cardiac Catheterization During Extracorporeal Membrane Oxygenation After Congenital Cardiac Surgery: A Multi-Center Retrospective Study.Pediatric cardiology · 2022Article
- The horizon of pediatric cardiac critical care.Frontiers in pediatrics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Worldwide, the use of Extracorporeal Membrane Oxygenation (ECMO) for cardiac failure has been steadily increasing in the neonatal population and has become a widely accepted modality. Especially in centers caring for children with (congenital) heart disease, ECMO is now an essential part of care available for those with severe heart failure as a bridge to recovery, long term mechanical support, or transplantation. Short-term outcomes depend very much on indication. Hospital survival is ~40% for all neonatal cardiac ECMO patients combined. ECMO is being used for pre- and/or post-operative stabilization in neonates with congenital heart disease and in neonates with medical heart disease such as myocarditis, cardiomyopathy or refractory arrhythmias. ECMO use during resuscitation (ECPR) or for sepsis is summarized elsewhere in this special edition of Frontiers in Pediatrics. In this review article, we will discuss the indications for neonatal cardiac ECMO, the difficult process of patients' selection and identifying the right timing to initiate ECMO, as well as outline pros and cons for peripheral vs. central cannulation. We will present predictors of mortality and, very importantly, predictors of survival: what can be done to improve the outcomes for your patients. Furthermore, an overview of current insights regarding supportive care in neonatal cardiac ECMO is given. Additionally, we will address issues specific to neonates with single ventricle physiology on ECMO, for example cannulation strategies and the influence of shunt type (Blalock-Taussig shunt vs. "right ventricle to pulmonary artery" shunt). We will not only focus on short term outcomes, such as hospital survival, but also on the importance of long-term neuro-developmental outcomes, and we will end this review with suggestions for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.