Evidence map›Paper›PMID 31497572›Full record

ArticleJournal of orthodontic science2019

Evaluation of enzyme activity and rate of tooth movement in corticotomy-accelerated tooth movement - A randomized clinical trial.

Gaurav Kumar, Gargee Rawat, Amrita, Vivek Kumar, Charanjit Singh Saimbi

Open access · goldAbstract read
In one paragraph

Article in Journal of orthodontic science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Gaurav KumarDepartment of Orthodontics and Dentofacial Orthopedics, Uttaranchal Dental and Medical Research Institute, Majri Grant, Doiwala, Dehradun, Uttarakhand, India.
Gargee RawatDepartment of Endodontics and Conservative Dentistry, Uttaranchal Dental and Medical Research Institute, Majri Grant, Doiwala, Dehradun, Uttarakhand, India.
AmritaDepartment of Periodontology, Uttaranchal Dental and Medical Research Institute, Majri Grant, Doiwala, Dehradun, Uttarakhand, India.
Vivek KumarDepartment of Periodontology, Hazaribag College of Dental Sciences and Hospital, Demotand, Hazaribag, Jharkhand, India.
Charanjit Singh SaimbiDepartment of Periodontology, Universal College of Medical Sciences, Bhairahwa, Nepal.
Uttaranchal University · INCollege of Medical Sciences · NPVinoba Bhave University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study was undertaken to evaluate the enzyme activity profiles in human saliva and gingival crevicular fluid (GCF) in accelerated tooth movement when compared with normal orthodontic tooth movement (OTM) in extraction cases. MATERIALS AND

methodsTwenty patients who required premolar extractions were treated with MBT mechanotherapy. They were divided into two equal groups: conventional (Group I) and corticotomy (Group II) which was performed on both the jaw sides before initiating retraction. GCF was collected from mesial and distal aspects of canine before initiation of retraction and at 7

resultsThe results showed that in Group I, the peak of aspartate aminotransferase (AST) and alkaline phosphatase (ALP) enzyme activity occurred on the 14

conclusionCorticotomy-accelerated tooth movement is a promising technique that has many applications in orthodontic treatment of adults as it helps overcome many of the current limitations of this treatment. The enzymatic activity signifies osteoclastic and osteoblastic activities, so ALP and AST from the saliva and GCF may potentially be used as biomarkers for monitoring corticotomy-assisted OTM.

Indexed as

Corticotomygingival crevicular fluidsalivatooth movement

Identifiers

PMID31497572
PMCPMC6702679
OpenAlexW2967185045

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.