Evidence map›Paper›PMID 31497569›Full record

ArticleImmunoTargets and therapy2019

Varicella zoster virus vaccines: an update.

Giovanni Gabutti, Niccolò Bolognesi, Federica Sandri, Caterina Florescu, Armando Stefanati

Open access · goldAbstract read
In one paragraph

Article in ImmunoTargets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Giovanni GabuttiDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-7259-4923
Niccolò BolognesiPostgraduate School of Hygiene and Preventive Medicine, University of Ferrara, Ferrara, Italy.ORCID 0000-0001-7465-8639
Federica SandriPostgraduate School of Hygiene and Preventive Medicine, University of Ferrara, Ferrara, Italy.ORCID 0000-0001-7865-4598
Caterina FlorescuPostgraduate School of Hygiene and Preventive Medicine, University of Ferrara, Ferrara, Italy.ORCID 0000-0003-4443-8461
Armando StefanatiDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.ORCID 0000-0001-6094-3439
University of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicella zoster virus (VZV) is the etiological agent of varicella, a highly infectious, self-limiting disease with serious complications. The decline in cell-mediated immunity (CMI) that occurs with aging or immunodepression causes a reactivation of the latent VZV as herpes zoster (HZ). Prevention of VZV through varicella vaccination strategies allows to avoid the primary infection in newborns and susceptible subjects. Available monovalent and combined VZV vaccines are effective, safe and generally well tolerated. Universal varicella vaccination has significantly impacted on incidence, complications and deaths related to this disease. Prevention of HZ through vaccination is a priority to avoid the significant burden of its incidence and complications. Currently two HZ vaccines are available. The recombinant zoster vaccine (RZV), approved by the FDA in 2017 and Zoster Vaccine Live (ZVL) licensed in the United States by the FDA in 2006. The advisory committee on immunization practices (ACIP) preferentially recommends RZV. ZVL remains an option for prevention of HZ in immunocompetent adults aged ≥60 years, although the CMI tends to wane a few years after vaccination.

Indexed as

epidemiologyrecombinant zoster vaccinevaccination strategiesvaricella vaccineZoster Vaccine Live

Identifiers

PMID31497569
PMCPMC6689529
OpenAlexW2965642600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.