ArticleVeterinary medicine (Auckland, N.Z.)2019
Infectious bursal disease virus in chickens: prevalence, impact, and management strategies.
Article in Veterinary medicine (Auckland, N.Z.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed, 105 citations in OpenAlex.
- A Naturally Occurring Novel Reassortant Strain of Infectious Bursal Disease Virus from Quails.Veterinary sciences · 2026Article
- Assessment of Immunological Interference Between Live Infectious Bursal Disease Virus and Avian Reovirus Vaccines in SPF Chickens.Animals : an open access journal from MDPI · 2026Article
- Pathogenicity, immunogenicity, and multi-organ tissue tropism of a novel variant infectious bursal disease virus in specific pathogen-free chickens.Veterinary world · 2026Article
- Chicken caspase-3 promotes IBDV replication via the cleavage of IRF7.Frontiers in microbiology · 2026Article
- Pathogenesis and Host Response to A3B4 and A3B2 Infectious Bursal Disease Virus Strains in Chickens.Transboundary and emerging diseases · 2026Article
- Deciphering the Natural Reassortment Dynamics of Infectious Bursal Disease Virus, Isolated from Field Outbreaks in Southern India, Through Complete Genome Sequencing.Pathogens (Basel, Switzerland) · 2025Article
- Infection Dynamics and Host Responses to Two IPNV Isolates in Liver of Atlantic Salmon (Pathogens (Basel, Switzerland) · 2025Article
- Development and Application of Indirect ELISA for IBDV VP2 Antibodies Detection in Poultry.Viruses · 2025Article
- Development of an in-house indirect ELISA kit for the serological detection of antibodies against infectious bursal disease in chickens.BMC veterinary research · 2025Article
- Biosecurity Implications, Transmission Routes and Modes of Economically Important Diseases in Domestic Fowl and Turkey.Veterinary sciences · 2025Review
- Evaluation of the immune responses of biological adjuvant bivalent vaccine with three different insertion modes for ND and IBD.Virulence · 2024Article
- Molecular characterization of circulating infectious bursal disease viruses in chickens from different Egyptian governorates during 2023.Virology journal · 2024Article
- Clarification of a unique mucosal vaccination route for improved systemic and mucosal immune response in broiler.Heliyon · 2024Article
- Genotype classification and pathogenicity of infectious bursal disease virus circulating in vaccinated broiler chicken farms.Veterinary research communications · 2024Article
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- Development of egg yolk-based polyclonal antibodies and immunoprophylactic potential of antigen-antibody complex against infectious bursal disease.Veterinary and animal science · 2024Article
- Effects of ultra-filtration purification of infectious bursal disease virus on immune responses and cytokine activation in specific pathogen free chickens.Veterinary research forum : an international quarterly journal · 2024Article
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- The effect of micronutrient supplementation on bioavailability, antioxidants activity, and weight gain in response to Infectious Bursal Disease vaccination in commercial broilers.Veterinary and animal science · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infectious bursal disease (IBD), also known as Gumboro disease, is a highly contagious, immunosuppressive disease of young chickens. Although first observed about 60 years ago, to date, the disease is responsible for major economic losses in the poultry industry worldwide. IBD virus (IBDV), a double-stranded RNA virus, exists as two serotypes with only serotype 1 causing the disease in young chickens. The virus infects the bursa of Fabricius of particularly the actively dividing and differentiating lymphocytes of the B-cells lineage of immature chickens, resulting in morbidity, mortality, and immunosuppression. Immunosuppression enhances the susceptibility of chickens to other infections and interferes with vaccination against other diseases. Immunization is the most important measure to control IBD; however, rampant usage of live vaccines has resulted in the evolution of new strains. Although the immunosuppression caused by IBDV is more directed toward the B lymphocytes, the protective immunity in birds depends on inducement of both humoral and cell-mediated immune responses. The interference with the inactivated vaccine induced maternally derived antibodies in young chicks has become a hurdle in controlling the disease, thus necessitating the development of newer vaccines with improved efficacy. The present review illustrates the overall dynamics of the virus and the disease, and the recent developments in the field of virus diagnosis and vaccine research.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.