Evidence map›Paper›PMID 31497286›Full record

ReviewF1000Research2019

Pulling in new directions: Myosin 2, Piezo, and metabolism.

Melissa A Quintanilla, John A Hammer, Jordan R Beach

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Melissa A QuintanillaCell and Molecular Physiology, Loyola University Chicago, Stritch School of Medicine, Center for Translational Research and Education, Maywood, IL, USA.
John A HammerCell and Developmental Biology Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Jordan R BeachCell and Molecular Physiology, Loyola University Chicago, Stritch School of Medicine, Center for Translational Research and Education, Maywood, IL, USA.ORCID 0000-0003-0633-4928
Loyola University Chicago · USNational Institutes of Health · US

Funding

Structure And Function Of Unconventional Myosins and CARMIL ProteinsZIAHL000514 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI HAMMER, JOHN A · 2009 to 2018
$9.6M
THE STRUCTURE AND SEQUENCE OF NON-MUSCLE MYOSIN GENESZ01HL000514 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI HAMMER, JOHN A · 1985 to 2008
$4.7M
Investigation of Myosin 2 Regulation by RLC Kinases During Dynamic Cellular ProcessesK22HL133150 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI BEACH, JORDAN · 2017 to 2019
$737k
Intramural NIH HHS Z01 HL000514Intramural NIH HHS ZIA HL000514NHLBI NIH HHS K22 HL133150
6 · The paper itself

Abstract

Myosin 2 plays a central role in numerous, fundamental, actin-based biological processes, including cell migration, cell division, and the adhesion of cells to substrates and other cells. Here, we highlight recent studies in which the forces created by actomyosin 2 have been shown to also impact tension-sensitive ion channels and cell metabolism.

Indexed as

ActomyosinCell AdhesionCell DivisionCell MovementHumansIon ChannelsMyosin Type IIActomyosinIon ChannelsMyosin Type IImetabolismmyosinpiezo

Identifiers

PMID31497286
PMCPMC6713065
OpenAlexW2969463366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.