Evidence map›Paper›PMID 31497214›Full record

ArticleAmerican journal of translational research2019

MicroRNA-30a-3p functions as a tumor suppressor in renal cell carcinoma by targeting WNT2.

Lingqi Liu, Liang Chen, Tianpeng Wu, Huijun Qian, Sixing Yang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lingqi LiuDepartment of Urology, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, China.
Liang ChenDepartment of Urology, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, China.
Tianpeng WuDepartment of Urology, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, China.
Huijun QianDepartment of Urology, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, China.
Sixing YangDepartment of Urology, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, China.
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expression and function of microRNA (miR)-30a-3p in several types of human cancer have been explored. However, the biological function of miR-30a-3p in renal cell carcinoma (RCC) remains largely unknown. In this study, we demonstrate that expression of miR-30a-3p is down-regulated in RCC tissues compared to adjacent normal tissues. Furthermore, ectopic expression of miR-30a-3p significantly suppressed the proliferation, migration, and invasion of a human RCC cell line

Indexed as

MicroRNA-30a-3pRenal cell carcinomaWNT2

Identifiers

PMID31497214
PMCPMC6731429
OpenAlexW2980960307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.