Evidence map›Paper›PMID 31497025›Full record

ReviewFrontiers in immunology2019

Parasite-Produced MIF Cytokine: Role in Immune Evasion, Invasion, and Pathogenesis.

Swagata Ghosh, Nona Jiang, Laura Farr, Renay Ngobeni, Shannon Moonah

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Crystal structure of Plasmodium vivax macrophage migration inhibitory factor.Acta crystallographica. Section F, Structural biology communications · 2026
    Article
  3. Article
  4. Transboundary and emerging diseases · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Malaria and dyserythropoiesis: a mini review.Frontiers in cellular and infection microbiology · 2025
    Review
  9. Structures of Trichomonas vaginalis macrophage migratory inhibitory factor.Acta crystallographica. Section F, Structural biology communications · 2024
    Article
  10. Science advances · 2024
    Article
  11. Review
  12. Analysis of the role ofJournal of veterinary research · 2024
    Article
  13. Protozoan-Derived Cytokine-Transgenic Macrophages Reverse Hepatic Fibrosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  14. Article
  15. Article
  16. Immune Mechanisms in Inflammatory Anemia.Annual review of immunology · 2023
    Review
  17. Review
  18. The many faces of parasite calreticulin.Frontiers in immunology · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Swagata GhoshDivision of Infectious Diseases and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, United States.
Nona JiangDepartment of Medicine, Yale University, New Haven, CT, United States.
Laura FarrDivision of Infectious Diseases and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, United States.
Renay NgobeniDepartment of Environmental, Water, and Earth Sciences, Tshwane University of Technology, Pretoria, South Africa.
Shannon MoonahDivision of Infectious Diseases and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, United States.

Funding

STRUCTURE/FUNCTION OF E HISTOLYTICA ADHERENCE LECTINR01AI026649 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI PETRI, WILLIAM A · 1989 to 2016
$6.1M
Global Infectious Disease Research Training Program at UVAD43TW006578 · FIC · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GUERRANT, RICHARD L · 2003 to 2018
$2.7M
Role of the Pro-inflammatory MIF Homolog of Entamoeba histolytica in ColitisK08AI119181 · NIAID · UNIVERSITY OF VIRGINIA · PI MOONAH, SHANNON · 2016 to 2020
$946k
FIC NIH HHS D43 TW006578NIAID NIH HHS K08 AI119181NIAID NIH HHS R01 AI026649
6 · The paper itself

Abstract

Protozoan parasites represent a major threat to health and contribute significantly to morbidity and mortality worldwide, especially in developing countries. This is further compounded by lack of effective vaccines, drug resistance and toxicity associated with current therapies. Multiple protozoans, including

Indexed as

Immune EvasionAnimalsHumansMacrophage Migration-Inhibitory FactorsParasitesMacrophage Migration-Inhibitory Factorscytokinehost-parasite interactionimmune evasionimmunopathologyimmunotherapeutic targetMIFprotozoan parasites

Identifiers

PMID31497025
PMCPMC6712082

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.