Evidence map›Paper›PMID 31497010›Full record

ReviewFrontiers in microbiology2019

Impacts of HIV Cure Interventions on Viral Reservoirs in Tissues.

Paul W Denton, Ole S Søgaard, Martin Tolstrup

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Functional Profile of CD8Frontiers in immunology · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Boosting the Immune System for HIV Cure: A γδ T Cell Perspective.Frontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Paul W DentonDepartment of Biology, University of Nebraska Omaha, Omaha, NE, United States.
Ole S SøgaardInstitute of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Martin TolstrupInstitute of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Aarhus University · DKUniversity of Nebraska at Omaha · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV reservoirs persist in infected individuals despite combination antiretroviral therapy and can be identified in secondary lymphoid tissues, in intestinal tissues, in the central nervous system as well as in blood. Clinical trials have begun to explore effects of small molecule interventions to perturb the latent viral infection, but only limited information is available regarding the impacts of HIV cure-related clinical interventions on viral reservoirs found in tissues. Of the 14 HIV cure-related clinical trials since 2012 that have evaluated the effects of small molecule interventions

Indexed as

HIV cureinterventional clinical trialslatencytissuesviral persistence

Identifiers

PMID31497010
PMCPMC6712158
OpenAlexW2968891329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.