ArticleJournal of medical biochemistry2019
Evaluation of Neutrophil-lymphocyte and Platelet-lymphocyte Ratios as Predictors of 30-day Mortality in Patients Hospitalized for an Episode of Acute Decompensated Heart Failure.
Article in Journal of medical biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Neutrophil to lymphocyte ratio (NLR) prognostic effects on heart failure; a systematic review and meta-analysis.BMC cardiovascular disorders · 2023Pooled it
- The impact of platelet-to-lymphocyte ratio on clinical outcomes in heart failure: a systematic review and meta-analysis.Therapeutic advances in cardiovascular diseasePooled it
- Neutrophil-to-Lymphocyte Ratio as a Predictor of Mortality and Clinical Outcomes in Heart Failure Patients.Cureus · 2025Review
- Prognostic potential of neutrophil-to-lymphocyte ratio for adverse outcomes in dilated cardiomyopathy: a retrospective cohort study.Scientific reports · 2025Article
- Assessment of the Severity of Intermediate Coronary Artery Stenosis Using the Systemic Inflammatory Response Index.Diagnostics (Basel, Switzerland) · 2025Article
- Inflammatory-Related Biomarkers in Patients Undergoing Percutaneous Transluminal Angioplasty for Femoropopliteal Artery Lesions.Acta Cardiologica Sinica · 2025Article
- Neutrophil-lymphocyte ratio (NLR) as an independent factor of 1-year mortality in patients with chronic heart failure with reduced ejection fraction.Cardiology journal · 2025Article
- Congestion and systemic inflammation in acute heart failure: correlations and prognostic role.Frontiers in cardiovascular medicine · 2025Article
- Association of platelet-to-lymphocyte ratio with 1-year all-cause mortality in ICU patients with heart failure.Scientific reports · 2024Article
- Article
- Prognostic roles of neutrophil-lymphocyte, monocyte-lymphocyte and platelet-lymphocyte ratios for long-term all-cause mortality in heart failure.International journal of cardiology. Heart & vasculature · 2024Article
- Insights into the Neutrophil-to-Lymphocyte Ratio and the Platelet-to-Lymphocyte Ratio as Predictors for the Length of Stay and Readmission in Chronic Heart Failure Patients.Diagnostics (Basel, Switzerland) · 2024Article
- Associations between static and dynamic changes of platelet counts and in-hospital mortality in critical patients with acute heart failure.Scientific reports · 2024Article
- Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Patients with Acute Decompensated Heart Failure: A Meta-Analysis.Journal of clinical medicine · 2024Review
- [Neutrophil-lymphocyte ratio as predictor of mortality in patients with necrotizing fasciitis].Revista medica del Instituto Mexicano del Seguro Social · 2024Observational
- The levels of systemic inflammatory markers exhibit a positive correlation with the occurrence of heart failure: a cross-sectional study from NHANES.Frontiers in cardiovascular medicine · 2024Article
- Article
- Association between neutrophil percentage-to-albumin ratio (NPAR), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and long-term mortality in community-dwelling adults with heart failure: evidence from US NHANES 2005-2016.BMC cardiovascular disorders · 2023Article
- Lipid and Haematologic Profiling of Regular Blood Donors Revealed Health Benefits.Journal of blood medicine · 2022Article
- U-shaped relationship between platelet-lymphocyte ratio and postoperative in-hospital mortality in patients with type A acute aortic dissection.BMC cardiovascular disorders · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the association between both neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) and 30-day mortality in patients hospitalized for an episode of acute decompensated heart failure (ADHF).
methods439 patients admitted to emergency department (ED) for an episode of ADHF. Clinical history, demographic, clinical and laboratory data recorded at ED admission and then correlated with 30-day mortality.
results45/439 (10.3%) patients died within 30 days from ED admission. The median values of NLR (4.1 vs 11.7) and PLR (159.1 vs 285.9) were significantly lower in survivors than in patients who died. The area under the ROC curve of NLR was significantly higher than that of the neutrophil count (0.76 vs 0.59; p<0.001), whilst the AUC of PLR was significantly better than that of the platelet count (0.71 vs 0.51; p<0.001). In univariate analysis, both NLR and PLR were significantly associated with 30-day. In the fully-adjusted multivariate model, NLR (odds ratio, 3.63) and PLR (odds ratio, 3.22) remained independently associated with 30-day mortality after ED admission.
conclusionsRoutine assessment of NLR and PLR at ED admission may be a valuable aid to complement other conventional measures for assessing the medium-short risk of ADHF patients.
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