ArticleOrthopedic research and reviews2019
The role of joint distraction in the treatment of knee osteoarthritis: a systematic review and quantitative analysis.
Article in Orthopedic research and reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Surgical treatments of bone marrow lesions.Journal of experimental orthopaedics · 2026Review
- Article
- Delaying arthroplasty: The potential of knee joint distraction in young osteoarthritis patients-A prospective case series.Journal of experimental orthopaedics · 2025Article
- [Treatment of rheumatoid arthritis of wrist using Ilizarov wrist joint distraction technique: a case report].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Article
- Two-year post-distraction cartilage-related structural improvement is accompanied by increased serum full-length SIRT1.Arthritis research & therapy · 2024Article
- Knee osteoarthritis pendulum therapy:Journal of orthopaedic translation · 2024Article
- Article
- Patients with advanced lateral osteoarthritis can return to sports and work after distraction arthroplasty plus lateral meniscal allograft transplantation combined with cartilage repair.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
- Insights into the present and future of cartilage regeneration and joint repair.Cell regeneration (London, England) · 2022Review
- Enhanced Extracellular Matrix Breakdown Characterizes the Early Distraction Phase of Canine Knee Joint Distraction.Cartilage · 2021Article
- Exploiting Joint-Resident Stem Cells by Exogenous SOX9 for Cartilage Regeneration for Therapy of Osteoarthritis.Frontiers in medicine · 2021Article
- Early-stage knee OA induced by MIA and MMT compared in the murine model via histological and topographical approaches.Scientific reports · 2020Article
- Subchondral Bone Remodeling: A Therapeutic Target for Osteoarthritis.Frontiers in cell and developmental biology · 2020Review
- Gene Expression Signatures of Synovial Fluid Multipotent Stromal Cells in Advanced Knee Osteoarthritis and Following Knee Joint Distraction.Frontiers in bioengineering and biotechnology · 2020Article
- Biologic Joint Restoration: A Translational Research Success Story.Missouri medicineArticle
- The Feasibility of Hinged Knee Arthrodiastasis for Cartilage Regeneration: A Systematic Review of the Literature.Strategies in trauma and limb reconstructionReview
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionKnee osteoarthritis is a major cause of pain and disability for which joint distraction is a potential treatment to delay the need for knee arthroplasty. This systematic review aims to assess the short- and long-term clinical and structural outcomes following knee joint distraction (KJD).
methodsMEDLINE, EMBASE, Scopus, and Web of Science databases were searched from the date of inception to 26th June 2019. Clinical studies investigating joint distraction for knee osteoarthritis with outcomes including ∆WOMAC index, ∆VAS pain score, and ∆joint space width were included. The review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) - CRD42018087032.
resultsNine studies comprising a total of 507 patients were included. There were four randomized controlled trials (RCTs), five open prospective cohort studies, and one case series. Overall, there were significant improvements in WOMAC index, VAS pain score and joint space width following KJD, which persisted up to 9 years. KJD also demonstrated comparable clinical outcomes with high tibial osteotomy and total knee arthroplasty.
conclusionThere is moderate quality evidence supporting the beneficial outcomes of joint distraction for knee osteoarthritis. Larger RCTs with longer follow-up (>1 year) are necessary to establish the true effect size of this procedure.
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