ArticleClinical, cosmetic and investigational dentistry2019
Wheat seeds can delay orthodontic tooth movement by blocking osteoclastogenesis in rats.
Article in Clinical, cosmetic and investigational dentistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Effect of psidium guajava fruit suspension on periodontium following orthodontic tooth movement in wistar rats-histologic findings.The Saudi dental journal · 2026Article
- Postorthodontic Relapse Prevention by Administration of Grape Seed (Vitis vinifera) Extract Containing Cyanidine in Rats.European journal of dentistry · 2019Article
- Different effects of soybean isoflavone genistein on transforming growth factor levels during orthodontic tooth movement among young and old rabbits.F1000Research · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe hormone estrogen can prevent osteoclast differentiation and suppress osteoclastic activity, which can prevent tooth relapse movement. Wheat seeds are a natural material containing phytoestrogens with similar characteristics to estrogen.
objectiveThis study intends to determine the influence of wheat seeds in reducing osteoclastogenesis following orthodontic tooth movement (OTM). MATERIALS AND
methodsForty male Sprague Dawley rats were used in this experimental study. The rats were divided into control and treatment groups (n=20). In both groups, the rat maxillary incisors were moved distally using a 0.012 U stainless steel orthodontic appliance with a 2 mm diameter coil and 5 mm wire length. The treatment group received wheat seeds at a dose of 0.6 gram/day. The animals were sacrificed at days 0, 1, 7, and 14 after using the orthodontic appliance (4 subgroups according to observations of days; n=5). RANKL and OPG expressions were determined from the gingival crevicular fluid (GCF) samples using ELISA analysis. Statistical analysis of the data collected was calculated with the independent sample
resultsAll the experimental procedures were well-tolerated and did not change the animals' weight. On days 7 and 14, the OTM rate of the treatment group was significantly lower than the control group (
conclusionWheat seeds can promote osteoclastogenesis inhibition and delay OTM.
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