Evidence map›Paper›PMID 31496801›Full record

ArticleCancer management and research2019

Postoperative metastasis prediction based on portal vein circulating tumor cells detected by flow cytometry in periampullary or pancreatic cancer.

Lianyuan Tao, Li Su, Chunhui Yuan, Zhaolai Ma, Lingfu Zhang, Shiping Bo, Yunyun Niu, Sijia Lu, Dianrong Xiu

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Prognostic Significance of Microvascular Invasion in Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lianyuan TaoDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, People's Republic of China.
Li SuMedical and Health Analytical Center, Peking University Health Science Center, Beijing 100191, People's Republic of China.
Chunhui YuanDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, People's Republic of China.
Zhaolai MaDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, People's Republic of China.
Lingfu ZhangDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, People's Republic of China.
Shiping BoDepartment of Clinical Research, Yikon Genomics Co. Ltd., Shanghai, People's Republic of China.
Yunyun NiuDepartment of Clinical Research, Yikon Genomics Co. Ltd., Shanghai, People's Republic of China.
Sijia LuDepartment of Clinical Research, Yikon Genomics Co. Ltd., Shanghai, People's Republic of China.
Dianrong XiuDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, People's Republic of China.
Peking University · CNSinotech Genomics (China) · CNHenan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the value of flow cytometry (FCM) detection of portal vein circulating tumor cells (CTCs) in predicting postoperative metastasis.

methodsSamples of portal venous blood and peripheral blood were collected from 39 patients during surgery, and CTCs were detected by FCM, with confirmation by laser confocal microscopy and single-cell sequencing.

resultsAmong all patients, a portal EpCAM+CD45- percentage ≥24.5×10

conclusionCTCs detected by FCM in portal venous blood are of significant value for the prediction of postoperative metastasis in pancreatic or periampullary tumors.

Indexed as

circulating tumor cellsflow cytometrymetastasespancreatic cancerportal vein

Identifiers

PMID31496801
PMCPMC6689556
OpenAlexW2964837608

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.