Evidence map›Paper›PMID 31496784›Full record

ArticlePharmacogenomics and personalized medicine2019

Association between polymorphisms of

Apichaya Puangpetch, Pornpen Srisawasdi, Weerapon Unaharassamee, Napa Jiratjintana, Somlak Vanavanan, Suweejuk Punprasit, Chalitpon Na Nakorn, Chonlaphat Sukasem, Martin H Kroll

Open access · goldAbstract read
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Polymorphisms of theJournal of clinical medicine · 2025
    Review
  3. Article
  4. Article
  5. Association ofPharmacogenomics and personalized medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Apichaya PuangpetchDivision of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Pornpen SrisawasdiDivision of Clinical Chemistry, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Weerapon UnaharassameeDepartment of Psychiatry, Somdet Chaopraya Institute of Psychiatry, Bangkok, Thailand.
Napa JiratjintanaDepartment of Psychiatry, Somdet Chaopraya Institute of Psychiatry, Bangkok, Thailand.
Somlak VanavananDivision of Clinical Chemistry, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Suweejuk PunprasitDivision of Clinical Chemistry, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Chalitpon Na NakornDivision of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Chonlaphat SukasemDivision of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Martin H KrollQuest Diagnostics, Secaucus, NJ 07094, USA.
Mahidol University · THSomdet Chaopraya Institute of Psychiatry · THQuest Diagnostics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether genetic polymorphisms related to pharmacodynamics with metabolic adverse effects, namely leptin promoter (

methodsA total of 180 patients treated with risperidone-based (

resultsThe prevalence of hyperglycemia was higher in patients receiving clozapine (64.0%) than in those receiving risperidone (30.8%). Among the candidate genes, only the

conclusionThe risk of type 2 diabetes mellitus is associated with the

Indexed as

atypical antipsychoticsdiabetes mellitusdopamine D2leptin promoterleptin receptorserotonin 5-HT2Aserotonin 5-HT2C

Identifiers

PMID31496784
PMCPMC6689662
OpenAlexW2965427742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.